Results 61 to 70 of about 92,286 (267)

Post-stroke Quality of Life Index: A quality of life tool for stroke survivors from Sri Lanka

open access: yesHealth and Quality of Life Outcomes, 2020
Background Burden of stroke is rising due to the demographic and epidemiological transitions in Sri Lanka. Assessment of success of stroke-management requires tools to assess the quality of life (QOL) of stroke survivors. Most of currently used QOL tools
P.K.B. Mahesh   +4 more
doaj   +1 more source

Applying the functional independence measure to the assessment of patients with mucopolysaccharidosis

open access: yes, 2020
Objective: To assess the functional independence of a group of patients with mucopolysaccharidosis using the Functional Independence Measure as a tool that accomplishes this purpose.
Almeida Matos, Marcos   +9 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Analysis-Oriented Stress–Strain Model for Prestressed FRP-Confined Circular Concrete

open access: yesBuildings
To develop an analysis-oriented stress–strain model for prestressed fiber-reinforced polymer (FRP)-confined circular concrete, the path-dependent responses of prestressed FRP-confined concrete and actively confined concrete were systematically ...
Zhaoqi Wu, Fan Hu, Quansong Meng
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Robust Consistency Checking for Modern Filesystems [PDF]

open access: yes, 2013
A runtime file system checker protects file-system metadata integrity. It checks the consistency of file system update operations before they are committed to disk, thus preventing corrupted updates from reaching the disk. In this thesis, we describe our
Sun, Kuei
core   +2 more sources

Inference on semiparametric models with discrete regressors [PDF]

open access: yes, 1993
We study statistical properties of coefficient estimates of the partially linear regression model when some or all regressors, in the unknown part of the model, are discrete. The method does not require smoothing in the discrete variables.
Delgado, Miguel A., Mora, Juan
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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