Results 71 to 80 of about 82,488 (269)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The geometry of independence tree models with hidden variables [PDF]

open access: yes, 2010
In this paper we investigate the geometry of undirected discrete graphical models of trees when all the variables in the system are binary, where leaves represent the observable variables and where the inner nodes are unobserved.
Zwiernik, Piotr, Smith, J. Q.
core  

Psychometric Properties and Factor Analysis of the Engagement and Independence in Dementia Questionnaire (EID-Q) [PDF]

open access: yes, 2018
Background/Aims: Independence and social engagement are important outcomes for people with dementia. The aim of this study was to conduct an in-depth psychometric assessment of the Engagement and Independence in Dementia Questionnaire (EID-Q), a measure ...
Orrell, Martin   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Monetary frameworks in developing countries : central bank independence and exchange rate arrangements

open access: yes, 2008
The objective of the thesis was to study monetary policy frameworks in developing countries. The thesis focused on three aspects of the monetary framework; the degree of central bank independence, the monetary policy strategy and the exchange rate ...
Maziad, Samar
core  

Psychometric Properties of the Make My Day Tool to Assess Perceived Performance of Children ’ s Daily Activities

open access: yesOpen Journal of Occupational Therapy, 2017
Background: No instrument with strong psychometric qualities exists to measure occupational performance in young children through child-reporting. We investigated the reliability and validity of the Make My Day (MMD) tool for children aged 4 to 7 years
Liron Or, Tsameret Ricon
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Does Instrument Independence Matter under the Constrained Discretionof an Inflation Targeting Goal? Lessons from UK Taylor Rule Empirics [PDF]

open access: yes
We investigate whether increased independence affects central bank behavior when monetary policy is already in an inflation targeting regime. Taking advantage of the recent UK experience to identify such an exogenous change, we estimate Taylor rules via ...
Alexander Mihailov
core  

Development of the Leiden Independence Questionnaire for Support Staff: a measure of staff behaviour regarding promoting independence of people with intellectual disabilities [PDF]

open access: yes, 2018
BACKGROUND: Support staff of adults with intellectual disability (ID) play an important role in promoting independence in home and community settings.
Dusseldorp, E.   +7 more
core   +1 more source

Numerical study of the discharge properties of atmospheric dielectric barrier discharge by using 200 kHz/13.56 MHz excitations

open access: yesAIP Advances, 2018
In this work involving an atmospheric dielectric barrier discharge system, the feasibility of independence control of key plasma parameters through strategic modulation of applied dual-frequency excitation sources is demonstrated.
F. R. Kong, Z. L. Zhang, B. H. Jiang
doaj   +1 more source

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