Results 51 to 60 of about 315,857 (305)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
npj Systems Biology and ApplicationsKnowledge bases have been instrumental in advancing biological research, facilitating pathway analysis and data visualization, which are now widely employed in the scientific community.
Xiao Chang +7 more
doaj +1 more source
Retrieval-Augmented Generation to Generate Knowledge Assets and Creation of Action Drivers
Applied SciencesThis article explores the application of Retrieval-Augmented Generation (RAG) to enhance the creation of knowledge assets and develop actionable insights from complex datasets. It begins by contextualising the limitations of large language models (LLMs),
Antony James +2 more
doaj +1 more source
Knowledge-based consistency index for fuzzy pairwise comparison matrices [PDF]
2017 IEEE International Conference on Fuzzy Systems (FUZZ-IEEE), 2017 Fuzzy AHP is today one of the most used Multiple Criteria Decision-Making (MCDM) techniques. The main argument to introduce fuzzy set theory within AHP lies in its ability to handle uncertainty and vagueness arising from decision makers (when performing pairwise comparisons between a set of criteria/alternatives). As humans usually reason with granular
Kubler, Sylvain +4 more
openaire +3 more sources
Knowledge base update model: an ONTO-AmazonTimber case study [PDF]
, 2017 Artigo apresentado no I Workshop de Informação, Dados e Tecnologia, realizado entre nos dias 04 e 06 de setembro de 2017, na cidade de Florianópolis (SC), no Auditório do Espaço Físico Integrado (EFI) da Universidade Federal de Santa Catarina (UFSC).O ...
Barbosa, Ademilson de Almeida +2 more
core
Towards Large-scale Inconsistency Measurement
, 2014 We investigate the problem of inconsistency measurement on large knowledge bases by considering stream-based inconsistency measurement, i.e., we investigate inconsistency measures that cannot consider a knowledge base as a whole but process it within a ...
A. Hunter +6 more
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
Revista Latino-Americana de Enfermagem, 2008 Nursing care to patients after total laryngectomy should be based on scientific knowledge. Evidence-based practice is a type of approach that stimulates the use of research results in clinical practice.
Mary Elizabeth de Santana +1 more
doaj +1 more source
Backwards State-space Reduction for Planning in Dynamic Knowledge Bases
, 2014 In this paper we address the problem of planning in rich domains, where knowledge representation is a key aspect for managing the complexity and size of the planning domain.
Senni, Valerio, Stawowy, Michele
core +2 more sources
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source