Results 81 to 90 of about 1,190,358 (265)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Longitudinal predictors of weapon involvement in middle adolescence: Evidence from the UK Millennium Cohort Study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 5-14, January 2023., 2023
Abstract This study uses longitudinal data from the UK Millennium Cohort Study (N = 13,277) to examine the childhood and early adolescence factors that predict weapon involvement in middle adolescence, which in this study is exemplified by having carried or used a weapon.
Aase Villadsen, Emla Fitzsimons
wiley   +1 more source

Hierarchical Neural Network for Extracting Knowledgeable Snippets and Documents [PDF]

open access: yesarXiv, 2018
In this study, we focus on extracting knowledgeable snippets and annotating knowledgeable documents from Web corpus, consisting of the documents from social media and We-media. Informally, knowledgeable snippets refer to the text describing concepts, properties of entities, or relations among entities, while knowledgeable documents are the ones with ...
arxiv  

Categorization and Pathology of Persian Stylistic Researches [PDF]

open access: yesLiterary Arts, 2014
In following article, surveys and researches about Persian style were categorized in two branches of historical and formalistic styles Mohammad Taghi Bahar founded stylistics as an autonomous knowledge by publishing his book, History of the evolution of ...
Maryam Dorpar
doaj   +1 more source

Determinación de la calidad de la formación universitaria en seis carreras de pedagogía y licenciatura en educación física de Chile (Determination of the quality of university training in six careers of pedagogy and degree in physical education of Chile)

open access: yesRetos: Nuevas Tendencias en Educación Física, Deportes y Recreación
Estudio descriptivo cuyo objetivo es determinar la calidad de la formación de los estudiantes de Pedagogía en Educación Física, en seis entidades universitarias, a partir del dominio de siete dimensiones asociadas a las Bases curriculares de Chile ...
Marcelo González Orb   +3 more
doaj   +1 more source

Informledge System: A Modified Knowledge Network with Autonomous Nodes using Multi-lateral Links [PDF]

open access: yesarXiv, 2011
Research in the field of Artificial Intelligence is continually progressing to simulate the human knowledge into automated intelligent knowledge base, which can encode and retrieve knowledge efficiently along with the capability of being is consistent and scalable at all times.
arxiv  

Learning by Asking Questions for Knowledge-based Novel Object Recognition [PDF]

open access: yesarXiv, 2022
In real-world object recognition, there are numerous object classes to be recognized. Conventional image recognition based on supervised learning can only recognize object classes that exist in the training data, and thus has limited applicability in the real world. On the other hand, humans can recognize novel objects by asking questions and acquiring
arxiv  

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