Results 71 to 80 of about 18,458 (301)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Fiscal consolidations in the Central and Eastern European countries [PDF]

open access: yes
We study fiscal consolidations in the Central and Eastern European countries and what determines the probability of their success. We define consolidation events as substantive improvements in fiscal balances adjusting for the impact of cyclical effects.
Nickel, Christiane   +2 more
core  

Democratic Consolidation: A Theory of Territorial Consolidation

open access: yesSSRN Electronic Journal, 2018
We are grateful for comments on earlier versions of this paper from Michael Coppedge, participants in the University of Amsterdam’s The Subnational State in Latin America Workshop, and members of the departments of political science at Central European University and the University of Missouri. This paper also benefitted from the research assistance of
McMann, Kelly, Maguire, Matthew
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Expansionary fiscal consolidations in Europe: part of conventional wisdom? [PDF]

open access: yes
In order to assess whether expansionary fiscal consolidations can be part of conventional wisdom, panel data models for private consumption are estimated for the EU15 countries, using annual data over the period 1970–2005. Three alternative approaches to
António Afonso
core  

Datalog+- Ontology Consolidation

open access: yesJournal of Artificial Intelligence Research, 2016
Knowledge bases in the form of ontologies are receiving increasing attention as they allow to clearly represent both the available knowledge, which includes the knowledge in itself and the constraints imposed to it by the domain or the users. In particular, Datalog± ontologies are attractive because of their property of decidability and the possibility
Cristhian Ariel David Deagustini   +3 more
openaire   +4 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The importance of institutions in expansionary fiscal consolidations. A critical assessment of non-Keynesian effects [PDF]

open access: yes, 2006
The short-term effects of fiscal consolidation have attracted an increasing attention from both the academia and policy makers in the recent years.
Benczes, István
core  

Fiscal Consolidation and Income Inequality in Latin America and the Caribbean

open access: yesEconomía
This paper estimates the effects of past fiscal consolidations in Latin America and the Caribbean (LAC) on income inequality. For the 13 LAC countries with fiscal consolidation episodes identified by the narrative approach, one percent of GDP fiscal ...
Takuji Komatsuzaki
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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