Results 91 to 100 of about 4,046 (259)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Structural Principles or Frequency of Use? An ERP Experiment on the Learnability of Consonant Clusters. [PDF]
Front Psychol, 2016 Wiese R +3 more
europepmc +1 more source
, 2008 This note aims to establish the nature of the consonant cluster -rdh- the character of which has not been commented on to my knowledge in modern scholarship.(1) Before dealing with the matter at hand it will be convenient to recapitulate the relevant requirements pertain ing to rhyming consonant clusters.(2)
openaire +2 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Correspondence of Consonant Clustering with Particular Vowels in German Dialects
LanguagesRecent work found a correspondence between consonant clustering probability in monosyllabic lexemes and the three vowel types, short and long monophthong and diphthong, in German dialects. Furthermore, that correspondence was found to be bound to a North–
Samantha Link
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Word-initial consonant clusters in Turkish: Evidence from transcription texts
Studia Linguistica Universitatis CracoviensisTranscription texts of Turkish record a phonetic phenomenon rarely attested in other Turkish sources: word-initial consonant clusters in items of non-Western origin.
Hilal Oytun Altun
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source