Results 101 to 110 of about 33,997 (302)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Analyzing the Pattern of L1 Sounds on L2 Sounds Produced by Javanese Students of Stkip PGRI Jombang

open access: yesIndonesian EFL Journal: Journal of ELT, Linguistics, and Literature, 2015
The studyconcerns on an analysis on the tendency of first language (L1) sound patterning on second language (L2) sounds done by Javanese students.Focusing on the consonant sounds, the data were collected by recording students’ pronunciationof English ...
Daning Hentasmaka
doaj   +2 more sources

The behavior of secondary consonant clusters in Swiss French child language

open access: yesNordlyd: Tromsø University Working Papers on Language & Linguistics, 2013
This paper aims to determine the behavior of secondary clusters in Swiss French child language and, in doing so, provide a first step towards the identification of the order of acquisition of primary and secondary clusters.
Helene N. Andreassen
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Effects of orthography on production and perception of English initial consonant clusters by L1 Persian speakers [PDF]

open access: yes, 2014
There are different views on how systems of speech perception and production function and if they are governed by the same system of rules and restrictions. The interrelation between learners’ perceptual and productive learning remains one of the central
Bavandpour, Parisa Karimi
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Temporal organization in sibilant-stop clusters in Moenat Ladin

open access: yesIsogloss
In this paper, we probe the temporal organization of word-initial consonant clusters in Moenat Ladin, a threatened and understudied minority Romance language in Italy. We focus on sibilant-stop clusters and hypothesize that the sibilant is external to a
Yifan Yang, Rachel Walker
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy