Results 101 to 110 of about 670,477 (293)

Phonotactics of Polish toponyms – consonant sequences

open access: yesLingVaria
This paper deals with consonant groups occurring at both edges of words in Polish toponyms. Consonant sequences are normal and typical of very few languages of the world. Therefore, their position in a word may matter. Interestingly, Polish clusters are
Krzysztof Jaskuła
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Croatian morphonotactic consonant clusters : a corpus-linguistic analysis

open access: yes, 2021
Morfonotaktika je novo i zanimljivo istraživačko područje unutar morfonologije. Temelji se na principima prirodne lingvistike, točnije na interakciji teorija prirodne fonologije i prirodne morfologije.
Vincelj, Dora
core  

Clusters and complex segments in Strict CV

open access: yesIsogloss
This article examines the extent to which complex segments are reanalayzable as two separate segments by examining /ʎ/ in two varieties of Occitan: Gascon and Languedocien.
Kaitlyn Owens
doaj   +1 more source

The consonant cluster rdh

open access: yes, 2008
This note aims to establish the nature of the consonant cluster -rdh- the character of which has not been commented on to my knowledge in modern scholarship.(1) Before dealing with the matter at hand it will be convenient to recapitulate the relevant requirements pertain ing to rhyming consonant clusters.(2)
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dystrybucja wykładnika stopnia wyższego -sz-/-ejsz-

open access: yesLingVaria
THE DISTRIBUTION OF THE MARKER OF DEGREE -SZ-/-EJSZ- Polish comparative of adjectives is marked by suffix -sz-, which has a variant -ejsz-. The distribution of the two variants is a matter of debate.
Rafał L. Górski
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Acquisition of Branching Onsets in Simultaneous French–Portuguese Bilingual Children: The Effect of Age, Language, Cluster Type, and Dominance

open access: yesLanguages
The literature on bilingual language development often reports cases of cross-linguistic interaction of the two languages being acquired. In this paper, we investigate possible cross-linguistic interaction outputs in the development of branching onsets ...
Letícia Almeida   +2 more
doaj   +1 more source

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