Results 41 to 50 of about 522 (205)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Students’ difficulties in pronouncing fricative consonant the fourth semester period 2018/2019 English Department students IAIN Padangsidimpuan [PDF]
, 2019 This thesis is a research about the Pronunciation of English Fricative by the students in the fourth semester of English Department in Tarbiyah and Teacher Training Faculty IAIN Padangsidimpuan academic year 2018/2019.
Situmeang, Imam Tarmizi
core
A Phono-Stylistic Analysis of Langston Hughes’ Poem “Harlem”
JL3T (Journal of Linguistics, Literature and Language Teaching)This research was utilized stylistic analysis tools at the phonological level in the poem titled “Harlem” by Langston Hughes. By leveraging the collective cultural scheme of the Harlem Renaissance, Hughes establishes a connection with the reader ...
Rahmadsyah Rangkuti, Susanty Tannada
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Trends in HearingAn objective method for assessing speech audibility is essential to evaluate hearing aid benefit in children who are unable to participate in hearing tests.
Varsha Pendyala +2 more
doaj +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The listening talker: A review of human and algorithmic context-induced modifications of speech
, 2014 Speech output technology is finding widespread application, including in scenarios where intelligibility might be compromised at least for some listeners by adverse conditions.
Aubanel, Vincent (R17640) +5 more
core +1 more source
Mechanisms of adaptation of Christian anthroponyms in Votic and Ingrian: a comparative study [PDF]
Слово.ру: балтийский акцентIn modern Finnic onomastics, the study of the pathways and mechanisms through which foreign borrowings are adapted in closely related languages has gained particular significance.
Dmitriev A.V.
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source