Results 61 to 70 of about 59,545 (260)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Changes in the McGurk Effect Across Phonetic Contexts [PDF]

, 2002
To investigate the process underlying audiovisual speech perception, the McGurk illusion was examined across a range of phonetic contexts. Two major changes were found.
Hampson, Michelle, Guenther, Frank H., Cohen, Michael A., Nieto-Castanon, Alfonso   +3 more
core  

An acoustic investigation of the developmental trajectory of lexical stress contrastivity in Italian [PDF]

, 2016
We examined whether typically developing Italian children exhibit adult-like stress contrastivity for word productions elicited via a picture naming task (n=25 children aged 3\u20135 years and 27 adults).
Arciuli, Joanne, Colombo, Lucia
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Phonological Development in the Early Speech of an Indonesian-German Bilingual Child [PDF]

, 2016
Current research in bilingual children’s language development with one language dominant has shown that one linguistic system can affect the other. This is called Crosslinguistic Influence (CLI).
Bosch, Bosch, Child, Child, Dardjowidjojo, Dardjowidjojo, De Houwer, De Houwer, Deuchar, Deuchar, Deutchar, Deutchar, Fikkert, Fikkert, Genesee, Genesee, Grosjean, Grosjean, I Wayan Pastika, Ingram, Ingram, Ingram, Ingram, Ingram, Ingram, Iverson, Iverson, Leopold, Leopold, Matthews, Matthews, Meisel, Meisel, Ni Luh Putu Sri Adnyani, Nicoladis, Nicoladis, Poulin, Poulin, Rowe, Rowe, Soriente, Soriente, Stempe, Stempe, Uiowa, Uiowa, Volterra, Volterra, Yulianto, Yulianto, ÖzCalişkan, ÖzCalişkan   +51 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

When orthography is not enough: the effect of lexical stress in lexical decision. [PDF]

, 2015
Three lexical decision experiments were carried out in Italian, in order to verify if stress dominance (the most frequent stress type) and consistency (the proportion and number of existent words sharing orthographic ending and stress pattern) had an ...
Colombo, Lucia, Simone, Sulpizio
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A Monophonemic Analysis of Prenasalized Consonants in Saramaccan

Journal of Ibero-Romance Creoles, 2013
This paper describes Saramaccan prenasalized consonants. We demonstrate that a phonetic analysis of consonant duration, and the duration of vowels preceding prenasalized consonants confirms phonological descriptions that characterize these units as ...
Yolanda Rivera Castillo
doaj  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source