Results 51 to 60 of about 53,993 (275)

Geminates and Picard Pronominal Clitic Allomorphy

open access: yesCatalan Journal of Linguistics, 2005
In this paper, we examine five pronominal clitics in Vimeu Picard with a geminate-consonant allomorph. Assuming a doubly-linked (non-moraic) representation of geminates, we attribute the four different patterns observed to four different underlying ...
Brian José, Julie Auger
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Language specific listening of Japanese geminate consonants: a cross-linguistic study [PDF]

open access: yesFrontiers in Psychology, 2014
Various aspects of linguistic experience influence the way we segment, represent, and process speech signals. The Japanese phonetic and orthographic systems represent geminate consonants (double consonants, e.g., /ss/, /kk/) in a unique way compared to other languages: one abstract representation is used to characterize the first part of geminate ...
Makiko eSadakata   +7 more
openaire   +8 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Preaspiration in Sienese Italian & Its Interaction with Stress in /VC:/ Sequences [PDF]

open access: yes, 2004
This paper reports some initial results from our investigation into effects of stress in /VC:/ sequences in Sienese Italian. Our spontaneous speech data show preaspiration in /VC:/ sequences, not previously reported for any variety of Italian.
Bel, Bernard   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

On Characterizing Sanskrit Gemination [PDF]

open access: yes, 2015
In Sanskrit, various intervocalic biconsonantal clusters are affected by gemination, which istypically summarized by phonetic treatises as follows. First, postvocalic consonants followedby another consonant is geminated as in sapta- `seven\u27 > sappta ...
Yasuko Suzuki, 鈴木 保子
core   +1 more source

Vowel duration, compression and lengthening in stressed syllables in Italian [PDF]

open access: yes, 2007
The focus of this study is on temporal organization, specifically of vowel duration, in stressed syllables in (standard) Italian. We investigate possible compression effects on the duration of stressed vowels according to wordposition (final, penult and ...
Hajek, John   +3 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

General linguistics and Indo-European reconstruction [PDF]

open access: yes, 2010
There is good reason to be ambivalent about the usefulness of general considerations in linguistic reconstruction. As a heuristic device, a theoretical framework can certainly be helpful, but the negative potential of aprioristic considerations must not ...
Kortlandt, Frederik H. H.
core  

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