Results 141 to 150 of about 135,367 (255)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Chaconnet, jousiork., Z730, g-molli

, 2009
Äänitetty radiosta.Digitoitu 9. 9. 2008Esittäjätiedot radiokuulutuksesta.Leonhardt-Consort (yhtye)
Purcell, Henry, säv.
core  

The reporting of CONSORT items and key feasibility elements in pilot and feasibility studies in hip and knee arthroplasty is suboptimal: a methodological survey. [PDF]

Pilot Feasibility Stud
Chung Z, Grant LA, Mbuagbaw L, Mokete L, Bhandari M, Thabane L.   +5 more
europepmc   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

The Waverly Consort, ensamble de música barroca (Estados Unidos)

, 1977
Concierto interpretado por el Waverly Consort. Este grupo está unánimemente reconocido como uno de los más prestigiosos conjuntos de cámara especializados en música medieval, del renacimiento y barroca.
The Waverly Consort - Ensamble de música barroca (Estados Unidos)
core  

Crossover Analysis Is Needed in Smartphone-Supported Vestibular Rehabilitation. [PDF]

JMIR Rehabil Assist Technol
Yan J, Yang K, Wang X, Su B.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The VAccine cLinical study reporting gUidEline: the VALUE checklist with explanation and elaboration. [PDF]

EBioMedicine
Duan Y, Ma Y, Shi L, Xu Z, Luo J, Moher D, Rodewald L, Shao R, Yu L, Li Y, Bian Z.   +10 more
europepmc   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Feasibility and impact of a large language model pipeline for surgical trial abstracts. [PDF]

NPJ Digit Med
Abiola OJ, Nepogodiev D, Glasbey J, Omar O, Linder C, Ledda V, Bhangu A.   +6 more
europepmc   +1 more source