Results 51 to 60 of about 336,808 (204)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Computationally Efficient Implementation of Convolution-based Locally Adaptive Binarization Techniques [PDF]

, 2012
One of the most important steps of document image processing is binarization. The computational requirements of locally adaptive binarization techniques make them unsuitable for devices with limited computing facilities.
A.S. Abutaleb, B. Gatos, D. Trier, D. Trier, D. Trier, J. Kittler, J. Sauvola, J.M. White, J.N. Kapur, J.R. Parker, K.T. Shin, K.V. Mardia, M.D. Dunlop, N. Otsu, W. Niblack, Y. Nakagawa   +15 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Using A Sliding Window Phase Matching Method for Imaging of GNSS Radio Occultation Signals

Remote Sensing, 2021
Global Navigation Satellite System Radio Occultation (GNSS-RO) is a technique used to sound the atmosphere and derive vertical profiles of refractivity.
Thomas Sievert, Joel Rasch, Anders Carlström, Vinícius Ludwig Barbosa, Mats I. Pettersson, Viet Vu   +5 more
doaj   +1 more source

Smoothed Particle Hydrodynamics in cosmology: a comparative study of implementations [PDF]

, 1998
We analyse the performance of twelve different implementations of Smoothed Particle Hydrodynamics (SPH) using seven tests designed to isolate key hydrodynamic elements of cosmological simulations which are known to cause the SPH algorithm problems.
Couchman, H. M. P., Pearce, F. R., Thacker, R. J., Thomas, P. A., Tittley, E. R.   +4 more
core   +4 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Zig-zag Sort: A Simple Deterministic Data-Oblivious Sorting Algorithm Running in O(n log n) Time

, 2014
We describe and analyze Zig-zag Sort--a deterministic data-oblivious sorting algorithm running in O(n log n) time that is arguably simpler than previously known algorithms with similar properties, which are based on the AKS sorting network. Because it is
Chvátal V., Goodrich M. T., Goodrich M. T., Pippenger N., Pratt V. R., S.   +5 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

GNU Octave and Python Implementation of Shor's r-Algorithm with Adaptive Step Control

Кібернетика та комп'ютерні технології, 2022
r-algorithms, or subgradient methods with dilation of space in the direction of the difference of two sequential subgradients, were proposed by N.Z.Shor in 1970 in his doctoral thesis. Respective software implementations proved to be competitive with the
Petro Stetsyuk, Aleksandr Pylypovskyi, Olha Khomiak   +2 more
doaj   +1 more source

Towards practical classical processing for the surface code

, 2012
The surface code is unarguably the leading quantum error correction code for 2-D nearest neighbor architectures, featuring a high threshold error rate of approximately 1%, low overhead implementations of the entire Clifford group, and flexible ...
Adam C. Whiteside, Austin G. Fowler, D. S. Wang, J. Edmonds, Lloyd C. L. Hollenberg, P. W. Shor, S. B. Bravyi   +6 more
core   +1 more source