Results 71 to 80 of about 336,808 (204)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Design and implementation of a constant-time fpga accelerator for fast elliptic curve cryptography
2016 International Conference on ReConFigurable Computing and FPGAs (ReConFig), 2016 62
Ay, Atıl U. +3 more
openaire +3 more sources
Faster quantum chemistry simulation on fault-tolerant quantum computers
New Journal of Physics, 2012 Quantum computers can in principle simulate quantum physics exponentially faster than their classical counterparts, but some technical hurdles remain. We propose methods which substantially improve the performance of a particular form of simulation, ab ...
N Cody Jones +6 more
doaj +1 more source
Influence of Signal Stationarity on Digital Stochastic Measurement Implementation [PDF]
Electronics, 2013 The paper presents the influence of signal stationarity on digital stochastic measurement method implementation. The implementation method is based on stochastic voltage generators, analog adders, low resolution A/D converter, and multipliers and ...
Ivan Župunski +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Transactional Conflict Problem
, 2018 The transactional conflict problem arises in transactional systems whenever two or more concurrent transactions clash on a data item. While the standard solution to such conflicts is to immediately abort one of the transactions, some practical systems ...
Alistarh, Dan +3 more
core +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Creating electronic oscillator-based Ising machines without external injection locking
Scientific Reports, 2022 Coupled electronic oscillators have recently been explored as a compact, integrated circuit- and room temperature operation-compatible hardware platform to design Ising machines.
Jaykumar Vaidya +2 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink +3 more
wiley +1 more source
Neuromorphic Computing and EngineeringProgress in neuromorphic computing requires efficient implementation of standard computational problems, like adding numbers. Here we implement a variety of sequential and parallel binary adders in the Lava software framework, and deploy them to the ...
Oskar von Seeler +5 more
doaj +1 more source