Results 61 to 70 of about 336,808 (204)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Dephasing due to background charge fluctuations
, 2003 In quantum computation, quantum coherence must be maintained during gate operation. However, in physical implementations, various couplings with the environment are unavoidable and can lead to a dephasing of a quantum bit(qubit).
Itakura, Toshifumi, Tokura, Yasuhiro
core +1 more source
A comparison of RESTART implementations [PDF]
, 1998 The RESTART method is a widely applicable simulation technique for the estimation of rare event probabilities. The method is based on the idea to restart the simulation in certain system states, in order to generate more occurrences of the rare event ...
Garvels, Marnix J.J., Kroese, Dirk P.
core +3 more sources
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Integer Factorization with a Neuromorphic Sieve
, 2018 The bound to factor large integers is dominated by the computational effort to discover numbers that are smooth, typically performed by sieving a polynomial sequence.
Monaco, John V., Vindiola, Manuel M.
core +1 more source
Implementation and validation of localized constant‐time correlated spectroscopy (LCT‐COSY) on a clinical 3T MRI scanner for investigation of muscle metabolism [PDF]
Journal of Magnetic Resonance Imaging, 2007 AbstractPurposeTo implement and evaluate a novel single‐volume two‐dimensional localized constant‐time‐based correlated spectroscopy (2D LCT‐COSY) sequence on a clinical 3T MR scanner. This sequence exhibits homonuclear decoupling along the F1 dimension, leading to improved spectral resolution compared to that of non‐constant‐time localized correlated ...
S Sendhil, Velan +7 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Feature Selection Criteria for Real Time EKF-SLAM Algorithm
International Journal of Advanced Robotic Systems, 2009 This paper presents a seletion procedure for environmet features for the correction stage of a SLAM (Simultaneous Localization and Mapping) algorithm based on an Extended Kalman Filter (EKF).
Fernando Auat Cheein +3 more
doaj +1 more source
A Posteriori error control & adaptivity for Crank-Nicolson finite element approximations for the linear Schrodinger equation [PDF]
, 2012 We derive optimal order a posteriori error estimates for fully discrete approximations of linear Schr\"odinger-type equations, in the $L^\infty(L^2)-$norm.
Katsaounis, Theodoros, Kyza, Irene
core +1 more source
Second-generation PLINK: rising to the challenge of larger and richer datasets [PDF]
, 2014 PLINK 1 is a widely used open-source C/C++ toolset for genome-wide association studies (GWAS) and research in population genetics. However, the steady accumulation of data from imputation and whole-genome sequencing studies has exposed a strong need for ...
Chang, Christopher C. +5 more
core +3 more sources