Results 61 to 70 of about 33,516 (251)
Verifying Constant-Time Implementations.
The constant-time programming discipline is an effective countermeasure against timing attacks, which can lead to complete breaks of otherwise secure systems. However, adhering to constant-time programming is hard on its own, and extremely hard under additional efficiency and legacy constraints.
José Bacelar Almeida +4 more
openaire +2 more sources
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Cache-Timing Attacks on RSA Key Generation
During the last decade, constant-time cryptographic software has quickly transitioned from an academic construct to a concrete security requirement for real-world libraries.
Alejandro Cabrera Aldaya +3 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Query and Depth Upper Bounds for Quantum Unitaries via Grover Search [PDF]
We prove that any $n$-qubit unitary can be implemented (i) approximately in time $\tilde O\big(2^{n/2}\big)$ with query access to an appropriate classical oracle, and also (ii) exactly by a circuit of depth $\tilde O\big(2^{n/2}\big)$ with one- and two ...
Gregory Rosenthal
doaj +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
CIDRarchy: CIDR-based ns-3 Routing Protocol for Large Scale Network Simulation
ns-3 is the successor of ns-2, the most popular network simulator. Network simulators such as ns-3 play an important role on understanding, designing, and building Internet systems.
Pedro Silva, Jaime Dias, Manuel Ricardo
doaj +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

