The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
Extreme gravitational lensing in vicinity of Schwarzschild-de Sitter black holes
, 2007 We have developed a realistic, fully general relativistic computer code to simulate optical projection in a strong, spherically symmetric gravitational field.
A. Einstein +12 more
core +1 more source
GenFloor: Interactive generative space layout system via encoded tree graphs
Frontiers of Architectural Research, 2021 Automated floorplanning or space layout planning has been a long-standing NP-hard problem in the field of computer-aided design, with applications in integrated circuits, architecture, urbanism, and operational research.
Mohammad Keshavarzi +1 more
doaj
Study the Thermal Effect of Twin Spool on the Dynamic Response and Whirl Orbit Using the Combined Finite Element – Transfer Matrix Method [PDF]
Engineering and Technology Journal, 2010 A study of the thermal effect on the critical speed and on the distribution of both the lateral and axial vibrations along the Dual rotor – system are considered .
doaj +1 more source
Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022 Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao +8 more
wiley +1 more source
Adversarial Data Programming: Using GANs to Relax the Bottleneck of Curated Labeled Data
, 2018 Paucity of large curated hand-labeled training data for every domain-of-interest forms a major bottleneck in the deployment of machine learning models in computer vision and other fields.
Balasubramanian, Vineeth N, Pal, Arghya
core +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
wiley +1 more source
Quantum Programming Made Easy [PDF]
, 2019 We present IQu, namely a quantum programming language that extends Reynold's Idealized Algol, the paradigmatic core of Algol-like languages. IQu combines imperative programming with high-order features, mediated by a simple type theory. IQu mildly merges
Paolini, Luca +2 more
core +2 more sources
Biosemiotic Entropy of the Genome: Mutations and Epigenetic Imbalances Resulting in Cancer
Entropy, 2013 Biosemiotic entropy involves the deterioration of biological sign systems. The genome is a coded sign system that is connected to phenotypic outputs through the interpretive functions of the tRNA/ribosome machinery.
Samuel S. Shepard +2 more
doaj +1 more source
{CtChecker}: A Precise, Sound and Efficient Static Analysis for Constant-Time Programming [PDF]
Timing channel attacks are emerging as real-world threats to computer security. In cryptographic systems, an effective countermeasure against timing attacks is the constant-time programming discipline.
Dang, Sixuan, Zhang, Danfeng, Zhou, Quan
core +1 more source