Results 51 to 60 of about 574,450 (294)

Complexity Theory, Game Theory, and Economics: The Barbados Lectures

open access: yes, 2020
This document collects the lecture notes from my mini-course "Complexity Theory, Game Theory, and Economics," taught at the Bellairs Research Institute of McGill University, Holetown, Barbados, February 19--23, 2017, as the 29th McGill Invitational ...
Roughgarden, Tim
core   +1 more source

Backdoors to Normality for Disjunctive Logic Programs [PDF]

open access: yes, 2013
Over the last two decades, propositional satisfiability (SAT) has become one of the most successful and widely applied techniques for the solution of NP-complete problems.
Fichte, Johannes Klaus, Szeider, Stefan
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Program transformations using temporal logic side conditions [PDF]

open access: yes, 2009
This paper describes an approach to program optimisation based on transformations, where temporal logic is used to specify side conditions, and strategies are created which expand the repertoire of transformations and provide a suitable level of ...
Aho A. V.   +20 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

On Integer Programming, Discrepancy, and Convolution

open access: yes, 2019
Integer programs with a constant number of constraints are solvable in pseudo-polynomial time. We give a new algorithm with a better pseudo-polynomial running time than previous results.
Jansen, Klaus, Rohwedder, Lars
core   +1 more source

Quantum Programming Made Easy [PDF]

open access: yes, 2019
We present IQu, namely a quantum programming language that extends Reynold's Idealized Algol, the paradigmatic core of Algol-like languages. IQu combines imperative programming with high-order features, mediated by a simple type theory. IQu mildly merges
Paolini, Luca   +2 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The power of linear programming for general-valued CSPs

open access: yes, 2014
Let $D$, called the domain, be a fixed finite set and let $\Gamma$, called the valued constraint language, be a fixed set of functions of the form $f:D^m\to\mathbb{Q}\cup\{\infty\}$, where different functions might have different arity $m$.
Kolmogorov, Vladimir   +2 more
core   +3 more sources

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