Results 61 to 70 of about 574,450 (294)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Programming an interpreter using molecular dynamics [PDF]

, 2007
PGA (ProGram Algebra) is an algebra of programs which concerns programs in their simplest form: sequences of instructions. Molecular dynamics is a simple model of computation developed in the setting of PGA, which bears on the use of dynamic data ...
C. A. Middelburg, C. A. Middelburg, C. A. Middelburg, J. A. Bergstra, J. A. Bergstra, J. A. Bergstra   +5 more
core   +4 more sources

Exploiting the structure effectively and efficiently in low rank matrix recovery

, 2018
Low rank model arises from a wide range of applications, including machine learning, signal processing, computer algebra, computer vision, and imaging science.
Absil, Agarwal, Ahmed, Alter, Amelunxen, Beck, Blanchard, Blumensath, Boumal, Boyd, Bunk, Cai, Cai, Cai, Cai, Cai, Cai, Candes, Candes, Candes, Candes, Candes, Candès, Candès, Candès, Candès, Carmon, Chandrasekaran, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Combettes, Davenport, Davenport, Ding, Donoho, Fazel, Ge, Ge, Ge, Goldberg, Gross, Hardt, Harrison, Huang, Jaggi, Jain, Jain, Ji, Jin, Keshavan, Kim, Kliesch, Koltchinskii, Krim, Kueng, Lanman, Li, Li, Lin, Ling, Ling, Liu, Liu, Lustig, Ma, Miao, Mishra, Mishra, Mishra, Mobahi, Mu, Negahban, Netrapalli, Ngo, Potter, Qu, Recht, Recht, Schermelleh, Srebro, Strohmer, Sun, Sun, Tanner, Tanner, Tao, Tharrault, Toh, Toh, Tomasi, Tu, Vandereycken, Wang, Wei, Wei, Wei, Wen, WenHuang, Xu, Yi, Zhang, Zhang, Zheng   +109 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Comprehensive Evaluation of OpenCL-based Convolutional Neural Network Accelerators in Xilinx and Altera FPGAs [PDF]

, 2016
Deep learning has significantly advanced the state of the art in artificial intelligence, gaining wide popularity from both industry and academia.
Kadetotad, Deepak, Kim, Minkyu, Linares Barranco, Alejandro, Ríos Navarro, José Antonio, Seo, Jae-Sun, Tapiador Morales, Ricardo   +5 more
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Modeling and ultrasonic examination of common carotid artery wall thickness changes

Archives of Acoustics, 2014
The paper describes the initial results of numeric analysis of plane-strain of a model of the human common carotid artery. The results of computer modeling were compared with the experimental data obtained by means of ultrasonic measurements of the ...
Zbigniew Trawiński, T. Powałowski
doaj  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source