Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Cefotatan; A New Corrosion Inhibitor for Corrosion of Mild Steel in Hydrochloric Acid Solution
The corrosion inhibition properties of cefotetan (CFT) for mild steel corrosion in HCl solution were analysed by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization methods.
Aditya Kumar Singh, Eno E. Ebenso
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Accurate Constant Phase Elements Dedicated for Audio Signal Processing [PDF]
This review paper introduces real-valued two-terminal fully passive RC ladder structures of the so-called constant phase elements (CPEs). These lumped electronic circuits can be understood as two-terminal elements described by fractional-order (FO) dynamics, i.e., current–voltage relation described by non-integer-order integration or derivation.
openaire +2 more sources
An InN/InGaN quantum dot nonlinear constant phase element
Abstract InN/InGaN quantum dots (QDs) are found to establish a nonlinear constant phase element (CPE) response over a wide frequency range, measured by electrochemical impedance spectroscopy (EIS). The intrinsic surface donors together with the near-surface electron accumulation layer form the fractional capacitor.
Peng Y. +4 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Effective Capacitance of a Constant Phase Element with Resistors in Series
The power of energy storage devices is characterized by capacitance and the internal resistance. The capacitance is measured on an assumption that the charges are stored at the electrode interface and the electric double layer behaves like an ideal capacitor.
openaire +1 more source
Effects of lead exposure on blood electrical impedance spectroscopy of mice
Background Lead is a nonessential heavy metal, which can inhibit heme synthesis and has significant cytotoxic effects. Nevertheless, its effect on the electrical properties of red blood cells (RBCs) remains unclear.
Binying Yang +4 more
doaj +1 more source
“Constant in Gain Lead in Phase” Element– Application in Precision Motion Control
This work presents a novel 'Constant in gain Lead in phase' (CgLp) element using nonlinear reset technique. PID is the industrial workhorse even to this day in high-tech precision positioning applications. However, Bode's gain phase relationship and waterbed effect fundamentally limit performance of PID and other linear controllers. This paper presents
Niranjan Saikumar +2 more
openaire +6 more sources

