Results 51 to 60 of about 7,169,794 (272)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Analog Modeling of Fractional-Order Elements: A Classical Circuit Theory Approach

open access: yesIEEE Access, 2021
In this paper a comprehensive procedure for the analog modeling of Fractional-Order Elements (FOEs) is presented. Unlike most already proposed techniques, a standard approach from classical circuit theory is applied.
Neven Mijat   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Early prediction of Li-ion cell failure from EIS derived from current–voltage time series

open access: yesJPhys Energy
The ability to reliably detect the forthcoming failure of a rechargeable cell without removing it from its normal operating environment remains a significant goal in battery research.
M T Wilson   +7 more
doaj   +1 more source

STRUCTURE CHARACTERIZATION OF CALCIUM DEFICIENT ELEMENT-SUBSTITUTED HYDROXYAPATITE WITH CONSTANT DOPANT RATIO OF DIFFERENT ELEMENTS

open access: yesThe Iraqi Journal of Agricultural science, 2020
The element-substituted calcium Deficient hydroxyapatite samples were synthesized using liquid-phase precipitation method. Different element ions (Mg+2, Zn+2, and Cu+2) were added at constant ratio (5% wt.).
Al-Sabbagh & et al.
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Correlation between Electrochemical Relaxations and Morphologies of Conducting Polymer Dendrites

open access: yesECS Advances
Conducting Polymer Dendrites (CPD) can engrave sophisticated patterns of electrical interconnects in their morphology with low-voltage spikes and few resources: they may unlock in operando manufacturing functionalities for electronics using metamorphism ...
Antoine Baron   +2 more
doaj   +1 more source

Relativistic transformation of phase-space distributions [PDF]

open access: yesAnnales Geophysicae, 2011
We investigate the transformation of the distribution function in the relativistic case, a problem of interest in plasma when particles with high (relativistic) velocities come into play as for instance in radiation belt physics, in the electron ...
R. A. Treumann   +4 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

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