Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Numerical study of creep in two-phase aggregates with a large rheology contrast : implications for the lower mantle [PDF]
International audienceIt is generally accepted that the Earth's lower mantle is dominated by two minerals, magnesiowustite (Mg, Fe)O (Mw) and (Mg, Fe)SiO3 perovskite (Mg-Pv) which are thought to exhibit very different rheological properties.
Boussuge, Michel +3 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cephamycin; A Novel Corrosion Inhibitor for Mild Steel Corrosion in HCl Acid Solution
The corrosion inhibition properties of cephamycin (CFC) for mild steel corrosion in HCl solution were analysed by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization methods.
Aditya Kumar Singh +4 more
doaj +1 more source
Quantum Ratchet Accelerator without a Bichromatic Lattice Potential
In a quantum ratchet accelerator system, a linearly increasing directed current can be dynamically generated without using a biased field. Generic quantum ratchet acceleration with full classical chaos [Gong and Brumer, Phys. Rev. Lett. 97, 240602 (2006)]
G. Casati, Jiangbin Gong, Jiao Wang
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Cefotatan; A New Corrosion Inhibitor for Corrosion of Mild Steel in Hydrochloric Acid Solution
The corrosion inhibition properties of cefotetan (CFT) for mild steel corrosion in HCl solution were analysed by electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization methods.
Aditya Kumar Singh, Eno E. Ebenso
doaj +1 more source
Resonant Characteristics of Rectangular Microcantilevers Vibrating Torsionally in Viscous Liquid Media [PDF]
The resonant characteristics of rectangular microcantilevers vibrating in the torsional mode in viscous liquid media are investigated. The hydrodynamic load (torque per unit length) on the vibrating beam due to the liquid was first determined using a ...
Brand, Oliver +5 more
core +3 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Early prediction of Li-ion cell failure from EIS derived from current–voltage time series
The ability to reliably detect the forthcoming failure of a rechargeable cell without removing it from its normal operating environment remains a significant goal in battery research.
M T Wilson +7 more
doaj +1 more source

