Results 41 to 50 of about 85,481 (262)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Single-Source Multi-Battery Solar Charger: Analysis and Stability Issues
In this paper, dynamic analysis of a multi-battery dual mode charger, powered by a single solar array and suitable for lead-acid and lithium-ion cell-based batteries is presented.
Alon Kuperman +4 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A mine-used DC chopper test platform based on energy self-circulation mode
For problems of large ripple of power supply, difficult selection of high-power load, low test efficiency and high test energy consumption existed in existing DC chopper test platform, a mine-used DC chopper test platform based on energy self-circulation
ZHANG Song +4 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
This paper develops a railway power module with wide range voltage (dc 60—dc 160 V) input and constant voltage output (24 V/10 A) . The power module adopts a two‐stage topology structure to realize voltage conversion.
Guowang Liu, Honglin Ouyang, Muxuan Xiao
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Maximum Efficiency Tracking for Dynamic WPT System Based on Optimal Input Voltage Matching
Wireless power transfer (WPT) technology has drawn much attention due to its advantages such as safety, convenience, and non-contact. For some movable devices such as intelligent inspection robot, the constant output voltage is very important to ensure ...
Hao He +6 more
doaj +1 more source

