Results 61 to 70 of about 471,152 (307)
, 2018 In a neuron with hyperpolarization activated current ($I_h$), the correct input frequency leads to an enhancement of the output response. This behavior is known as resonance and is well described by the neuronal impedance.
Ceballos, Cesar C. +3 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modulator for tone and binary signals [PDF]
, 1975 Tones and binary information are transmitted as phase variations on a carrier wave of constant amplitude and frequency. The carrier and tones are applied to a balanced modulator for deriving an output signal including a pair of sidebands relative to the ...
Fitch, E. J. +2 more
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A Constant-Power Battery Charger with Inherent Soft Switching and Power Factor Correction [PDF]
, 2003 A battery charging circuit, which operates as a constant power source, is proposed in this paper. By maintaining a constant output power throughout the charging process, the circuit reduces the size of thermal installation which would normally be ...
Pong, BMH, Poon, NK, Tse, CK
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Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Constant Voltage Output in Two-Chamber Microbial Fuel Cell Under Fuzzy PID Control
International Journal of Electrochemical Science, 2013 Microbial fuel cells (MFCs) have been receiving more and more attention in simultaneous treatment of wastewater and energy recovery. Past research has been mainly in experiments. Modelling and controlling are new subjects emerging recently.
Minxiu Yan, Liping Fan
doaj +1 more source
Pulse transducer with artifact signal attenuator [PDF]
, 1980 An artifact signal attenuator for a pulse rate sensor is described. The circuit for attenuating background noise signals is connected with a pulse rate transducer which has a light source and a detector for light reflected from blood vessels of a living ...
Cash, W. H., Jr., Polhemus, J. T.
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
, 1972 A thin film gauge for use in measuring distributed convective heat transfer rates occurring along given surfaces, is described. The gauge is particularly suited to measuring test surfaces in the air stream of a wind tunnel.
Mcronald, A. D.
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