Results 21 to 30 of about 56,035 (261)

Novel Interface for Simulation of Assembly Operations in Virtual Environments

open access: yesAdvances in Electrical and Computer Engineering, 2013
The objective of this paper is to propose a new interface based on human gestures for simulation of assembly operation inside virtual environments. Using as a guide the current context for assembly simulation, we have analyzed the existing techniques ...
CRACIUN, E.-G.   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Citizen Expectations of a Constituent Assembly: The Chilean Experience [PDF]

open access: yes, 2021
Las expectativas que tiene Chile respecto al desempeño y ejercicio del poder constituyente de la Convención Constitucional que se inició el 4 de julio de 2021, no se diferencia de lo que parte de la experiencia comparada en Latinoamérica a esperado de ...
Escudero, María Cristina
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

THE CONSTITUENT ASSEMBLY OF GEORGIA ACCORDING TO NOE JORDANIA’S CONCEPT

open access: yes, 2021
ეძღვნება ივანე ჯავახიშვილის დაბადებიდან 145 წლის იუბილესFrom the very beginning, the Georgian political elite believed that the national council (hereinafter – the parliament) was not a legitimate legislative body, since it had not been elected by the ...
შველიძე, დიმიტრი
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Elections to All-Russian Constituent Assembly in Terek Region: March — December 1917

open access: yesНаучный диалог
This article examines the elections to the Constituent Assembly of 1917 in the Terek region. The study of this process provides valuable historical insights that can inform contemporary electoral practices, thus representing a significant scholarly issue.
S. V. Darchieva
doaj   +1 more source

(The mutual influence between the constitutional rule and international custom) [PDF]

open access: yesالرافدین للحقوق
The subject of the research is the mutual influence between the constitutional rule and international custom, the reality of the role played by some international legal rules represented by the original sources, including customary international rules ...
Hind Alwash
doaj   +1 more source

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