Results 31 to 40 of about 54,888 (266)

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Nueva Constitución y Asamblea Constituyente en Chile // New Constitution and Constituent Assembly in Chile

Revista de Derecho Político, 2014
En este trabajo se aborda el debate abierto en Chile sobre la necesidad o no de convocar una Asamblea constituyente para elaborar una nueva Constitución.
Francisco Zúñiga Urbina
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Constituent power and the feminist approach: an analysis of the Constituent Assembly in Brazil in 1987

Revista de Investigações Constitucionais
Constituent power is understood as the power to bring about constitutional change. In modern constitutionalism, ‘the people’ are the legitimate holders of this power and they can exercise their constituent power to write a new constitution.
Thais Andrade Brugnerotto, Ruth Houghton
doaj   +1 more source

Novel Interface for Simulation of Assembly Operations in Virtual Environments

Advances in Electrical and Computer Engineering, 2013
The objective of this paper is to propose a new interface based on human gestures for simulation of assembly operation inside virtual environments. Using as a guide the current context for assembly simulation, we have analyzed the existing techniques ...
CRACIUN, E.-G., GRISONI, L., PENTIUC, S.-G., RUSU, I.   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

O corporativismo como estratégia: governo Vargas, apoio social e a constituinte de 1933-1934

Ler História, 2019
The article explores the connection between the building of a support base for the regime established in Brazil in 1930 and the creation of corporatist institutions, notably the representation of different social groups and official trade unionism.
Marco Aurélio Vannucchi
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

As disputas políticas e a constituinte brasileira de 1987-1988: projetos, sonhos e utopias

Ler História, 2019
This article aims to reflect on the struggles that occurred in Brazil in the context of drafting the Constitution of 1988. Its purpose is to analyze the political disputes at the moment of the country’s redemocratization, highlighting especially two ...
Fernando Perlatto
doaj   +1 more source