Results 41 to 50 of about 54,888 (266)
Filament assembly of the C. elegans lamin in the absence of helix 1A
Nucleus, 2022 Lamins are the major constituent of the nuclear lamina, a protein meshwork underlying the inner nuclear membrane. Nuclear lamins are type V intermediate filaments that assemble into ~3.5 nm thick filaments.
Rebecca de Leeuw +3 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Cadernos de Campo, 2012 During the provisional governments of Getúlio Vargas and José Linhares, respectively in 1933 and 1945, a group of laws was issued whose function was, mainly, to define procedures that could regulate the taking up office of the Contituent Assemblies of ...
Adriana Duarte de Souza Carvalho +1 more
doaj
THE SOVIET HISTORIOGRAPHY OF THE SOLDIER UNREST IN THE FIRST PERIOD OF THE FRENCH REVOLUTION
Вестник Брянского государственного университетаThe issue of discontent among the rank and file and non-commissioned officers of the French Army in the first period of the Revolution and the unrest caused by it in 17891791 has been relatively rarely mentioned in historical works since1917.
Blumenau S.F.
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Nature Communications, 2020 Characterizing the assembly of the nuclear pore complex (NPC) remains challenging. Here, the authors develop a set of nanobodies that recognize seven constituent nucleoporins, study their binding characteristics, and apply them to probe accessible and ...
Sarah A. Nordeen +5 more
doaj +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
C. M. TALLEYRAND AND THE MODERNIZATION OF THE FRENCH FINANCIAL SYSTEM IN 1789 - 1791.
Вестник Брянского государственного университетаThe article examines the financial problems of France in the period 1789-1791. At the end of the Ancien Regime, the state faced very serious problems in the financial sector: a huge public debt and an ineffective fiscal system.
Samsarov A.I.
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A Constituent Assembly Only in Name?: Part I on Venezuela’s Constituent Assembly
, 2017 Verfassungsblog: On Matters ...
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source