Results 71 to 80 of about 7,203,774 (334)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The cult of the written constitution and the dilemmas of constitutional changes: scientific approaches and practice of deliberative constitutionalism

open access: yesПравоприменение
The subject. The article discusses the scientific foundations of the cult of a written constitution, the relationship between the principles of the supremacy of the constitution and fidelity to the constitution, on the one hand, and the forms and methods
I. A. Kravets
doaj   +1 more source

Conformal Symmetry and Pion Form Factor: Soft and Hard Contributions

open access: yes, 2007
We discuss a constraint of conformal symmetry in the analysis of the pion form factor. The usual power-law behavior of the form factor obtained in the perturbative QCD analysis can also be attained by taking negligible quark masses in the nonperturbative
Choi, H. -M., Ji, C. -R.
core   +1 more source

QCD Constituent Counting Rules for Neutral Vector Mesons [PDF]

open access: yes, 2017
QCD constituent counting rules define the scaling behavior of exclusive hadronic scattering and electromagnetic scattering amplitudes at high momentum transfer in terms of the total number of fundamental constituents in the initial and final states ...
Brodsky, Stanley J.   +2 more
core   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

South Africa’s social contract: the Economic Freedom Fighters and the rise of a new constituent power?

open access: yesActa Academica, 2018
Taking the South African constitution as an eminent symbol of the South African social contract, and noting the opinion of many that the contract has failed to deliver, this article explores the concept of the social contract in South Africa by ...
Rachel Adams
doaj   +3 more sources

El poder Constituyente de los Pueblos del Mundo

open access: yesPensamiento Jurídico, 2015
Este artículo analiza y reivindica el poder constituyente de los pueblos en la escena internacional. Observa cómo, en un mundo globalizado, la capacidad de acción de una gran mayoría de Estados parece atrapada en el discurso neoliberal, en democracias ...
Antonio José Rengifo Lozano
doaj  

The inconsistencies of the doctrine of unconstitutional constitutional amendments

open access: yesRevista de Investigações Constitucionais
This article critically examines Yaniv Roznai’s influential doctrine of unconstitutional constitutional amendments (UCA), which aims to reconcile judicial review of constitutional amendments with democracy by grounding both amendment limits and judicial ...
Diego Pardo-Alvarez
doaj   +1 more source

The constituent power and transitional justice in Brazil

open access: yesRevista do Direito Público, 2015
This article discusses two major fundamental theoretical issues in the formation of the modern state that are intertwined. The production of new constitutions, the change of the rule of recognition that allows the entry of statutes in the legal system as
Bruno Meneses Lorenzetto, Katya Kozicki
doaj   +1 more source

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