Results 51 to 60 of about 10,381 (250)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
How can artificial neural networks approximate the brain?
Frontiers in Psychology, 2023 The article reviews the history development of artificial neural networks (ANNs), then compares the differences between ANNs and brain networks in their constituent unit, network architecture, and dynamic principle.
Feng Shao, Zheng Shen
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Representation, reappropriation: The body of the image in the mystical text of Teresa of Avila [PDF]
Filozofija i Društvo, 2019 What follows is but the attempt to draw the lessons from the mystical and visionary text of Teresa of Ávila in order to consider today issues that concern us, questions that are asked of Aesthetics, and not only as theoretical discipline that ...
Santos Guerrero Julián
doaj +1 more source
Frontiers in Oncology, 2022 The incidence of multiple primary carcinomas (MPCs), which are defined as two or more malignancies detected in an individual person, is gradually increasing around the world.
Yongxing Du +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2010 Georgakopoulos T, Skopeteas S. Projective vs. interpretational properties of nuclear accents and the phonology of contrastive focus in Greek. Linguistic Review. 2010;27(3):319-346.Nuclear accents have two interesting properties.
Georgakopoulos, Thanasis +4 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Élisée Reclus e os Estados Unidos
Terra Brasilis, 2016 Comment les convictions intimes influencent-elles l’écriture d’une œuvre scientifique? Leur caractère “subjectif” permet-il de franchir les préjugés du temps et ceux des collègues, pour enrichir le savoir “objectif” par un travail original? Ces questions
Ronald Creagh
doaj +1 more source