Results 91 to 100 of about 1,853,445 (346)
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source
Dr. Patrick T. Conley on the Law and Order Constitution [PDF]
, 2012 In this interview, Dr. Patrick T. Conley, constitutional historian and Dorr scholar, discusses the deficiencies of the Law & Order Constitution of 1843, the provisions of the People\u27s Constitution of 1841, and his personal involvement in the Rhode ...
Conley, Patrick T.
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Application of TCM constitution in lifetime health maintenance
Journal of Traditional Chinese Medical Sciences, 2018 Healthy full life cycle has become an important national strategy, which indicates that attention needs to be given to human health throughout the life course.
Qi Wang +7 more
doaj +1 more source
The Constitution of the Elements [PDF]
Nature, 1919 SINCE my last letter under the above title in NATURE of July 1, experiments have been made with a few more elements. The work has been progressively more and more difficult, for it has not been easy to find volatile compounds suitable for use, and when found the very objectionable chemical properties of some of them have led to experimental trouble and
openaire +4 more sources
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Scientific ReportsAllergic rhinitis (AR) is a common immune-mediated chronic inflammatory disease with a complex pathogenesis involving multiple responses of the immune system and epigenetic changes.
Yumei Zhou +7 more
doaj +1 more source
Casino Gambling Will Create More Costs Than Benefits in New York State [PDF]
, 2013 In November 2013, New York State voters will decide whether to amend the state constitution to expand casino gambling. Currently, the state has five casinos run by Indian tribes.
Cimasi, Michael, Leonard, Alexis
core +1 more source