Results 101 to 110 of about 2,120,912 (382)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Application of TCM constitution in lifetime health maintenance

open access: yesJournal of Traditional Chinese Medical Sciences, 2018
Healthy full life cycle has become an important national strategy, which indicates that attention needs to be given to human health throughout the life course.
Qi Wang   +7 more
doaj   +1 more source

Is the Constitution Libertarian? [PDF]

open access: yes, 2009
Ever since Justice Holmes famously asserted that “the Constitution does not enact Mr. Herbert Spencer’s Social Statics,” academics have denied that the Constitution is libertarian.
Barnett, Randy E
core   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Alterations in gut microbiota and urine metabolomics in infants with yin-deficiency constitution aged 0–2 years

open access: yesHeliyon, 2023
Background: Based on the constitution theroy, infants are classified into balanced constitution (BC) and unbalanced constitution. Yin-deficiency constitution (YINDC) is a common type of unbalanced constitutions in Chinese infants.
Haihong Zhao   +7 more
doaj  

The Original Theory of Constitutionalism [PDF]

open access: yes, 2014
The U.S. Constitution embodies a conception of democratic sovereignty that has been substantially forgotten and obscured in today’s commentary. Recovering this original idea of constitution-making shows that today’s originalism is, ironically, unfaithful
Grewal, David Singh, Purdy, Jedediah
core   +1 more source

Association of TCM body constitution with insulin resistance and risk of diabetes in impaired glucose regulation patients

open access: yesBMC Complementary and Alternative Medicine, 2017
BackgroundImpaired glucose regulation (IGR) patients have increased risk of type 2 diabetes mellitus (T2DM). Identifying relevant risk factors in IGR subjects could facilitate early detection and prevention of IGR progression to diabetes.
H. You, Tong Zhang, W. Feng, Yunfeng Gai
semanticscholar   +1 more source

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

The Growth of General Election as an Implementation of Democracy and Constitution in Indonesia since Parliamentary Democracy Era until Reformation Era [PDF]

open access: yes, 2007
The objectives of this research are (first) to know General election growth as an implementation of democracy in Indonesia specially as an empirical description of General Election since Parliamentary Era until Reformation Era ...
Aminoto,, Mahfud MD, Moh., Mulyanto,
core  

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

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