Results 101 to 110 of about 1,805,078 (297)

Quintessential Elements of Meaningful Constitutions in Post-Conflict States [PDF]

open access: yes, 2008
This examination compares several successful constitutions formulated to govern countries just formed from the conclusion of armed conflicts (including the U.S.).
Van Alstyne, William W.
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Combining AlphaFold—based AI docking with omics technologies preliminarily unveils the mechanism of Guominkang in treating allergic rhinitis

open access: yesScientific Reports
Allergic rhinitis (AR) is a common immune-mediated chronic inflammatory disease with a complex pathogenesis involving multiple responses of the immune system and epigenetic changes.
Yumei Zhou   +7 more
doaj   +1 more source

Ideology, constitutional culture and institutional change: the EU constitution as reflection of Europe’s emergent postmodernism [PDF]

open access: yes
Using the example of the European Constitution, this paper argues that ideology plays a much more important role in institutional change than has been indicated hitherto in the literature.
Nikolay Wenzel
core  

What Is Constituted in Self-Constitution? [PDF]

open access: yes, 2002
A subject who has a self-transformation behind herself—say, a conversion to Catholicism—may say of herself "before transforming myself, I was a different person�. How are we to understand such a claim?
Gunnarsson, Logi
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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