Results 141 to 150 of about 1,871,925 (346)
The Constitution and Legislative History [PDF]
, 2014 In this article, the author provides an extended analysis of the constitutional claims against legislative history, arguing that, under textualists’ own preference for constitutional text, the use of legislative history should be constitutional to the ...
Nourse, Victoria
core +2 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The Hungarian Constitutional Court and Constitutional Identity
, 2017 Verfassungsblog: On Matters ...
openaire +3 more sources
Dr. Patrick T. Conley on the Law and Order Constitution [PDF]
, 2012 In this interview, Dr. Patrick T. Conley, constitutional historian and Dorr scholar, discusses the deficiencies of the Law & Order Constitution of 1843, the provisions of the People\u27s Constitution of 1841, and his personal involvement in the Rhode ...
Conley, Patrick T.
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
A note from the editors: the state of the political constitution [PDF]
, 2013 The revival of the political constitution has come about in parallel with two developments, one in constitutional practice and the other in political theory.
Goldoni, M., McCorkindale, C.
core
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Law\u27s Constitution: A Relational Critique [PDF]
, 2002 It is a simple fact: we begin from others. Without others we, quite literally, could not live, feel, be born. Every mother, every mother\u27s partner, every father, every child, knows this.
Nourse, Victoria
core +1 more source