Results 51 to 60 of about 1,871,925 (346)

Gastric cancer fibroblasts affect the effect of immunotherapy and patient prognosis by inducing micro-vascular production

open access: yesFrontiers in Immunology
IntroductionImmunotherapy is critical for treating many cancers, and its therapeutic success is linked to the tumor microenvironment. Although anti-angiogenic drugs are used to treat gastric cancer (GC), their efficacy remains limited.
Yan Xia   +8 more
doaj   +1 more source

Damp-heat constitution influences gut microbiota and urine metabolism of Chinese infants

open access: yesHeliyon, 2023
Background: As an increasingly popular complementary and alternative approach for early detection and treatment of disease, traditional Chinese medicine constitution (TCMC) divides human beings into those with balanced constitution (BC) and unbalanced ...
Haihong Zhao   +9 more
doaj   +1 more source

Material Constitution [PDF]

open access: yes, 2019
An annotated bibliography of important works on material ...
Korman, Daniel Z.
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Constitution for Europe and other constitutions [PDF]

open access: yesEuropean Constitutional Law Review, 2005
The spring of 2005 saw major set-backs for the Treaty of Rome of 29 October 2004, establishing what it calls ‘a Constitution for Europe’. On 29 May, the French rejected the Treaty in their referendum by 54,8% (turnout 70%). Then the Dutch rejected it on 1 June by an even more massive 61,7% (turnout 63%).
Eijsbouts, W.T., Besselink, L.F.M.
openaire   +3 more sources

What’s left of the political constitution? [PDF]

open access: yes, 2013
This paper argues that we should move on from what has become a rather outdated contrast between the political constitution and the legal constitution.
Tomkins, A.
core  

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution

open access: yesChinese Medicine
Background Traditional Chinese Medicine (TCM) defines constitutions which are relevant to corresponding diseases among people. As one of the common constitutions, Yin-deficiency constitution influences a number of Chinese population in the disease onset.
Jing Li   +4 more
doaj   +1 more source

The Lisbon Treaty: a constitutional document, not a constitution–a British perspective [PDF]

open access: yes, 2010
The European Union has undergone a constitutional transformation in the past half century. It has evolved from its origins as the European Economic Community, promoting economic integration, into a supranational polity that has come to be perceived in
Bremner, Phillip
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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