Results 91 to 100 of about 46,692 (260)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
On the constitutive relations for second sound in thermo-electroelasticity
Archives of Mechanics, 2011 In papers [1] and [2] of 1982, Coleman, Fabrizio and Owen gave a derivation of implications of the second law of thermodynamics to describe second sound in rigid heat conductors, by using a natural extension to anisotropic media of the well-known ...
A. Montanaro
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Extended Elastoplastic Constitutive Equation with Tangential Stress Rate Effect [PDF]
, 1997 The extension of the elastoplastic constitutive equation so as to describe the plastic stretching due to the stress rate component tangential to the yield or loading surface has been one of the most pressing problems in the elastoplasticity. To this aim,
Hashiguchi, Koichi +5 more
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Numerical Simulation of Three-Dimensional Free Surface Flows Using the K-BKZ-PSM Integral Constitutive Equation. [PDF]
Polymers (Basel), 2023 Bertoco J +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Superplastic GBS Constitutive Equation Incorporating Average Grain Misorientation Dependence [PDF]
, 2019 Recent Al7075 severe friction stir processing (FSP) data gave new insights regarding the relationship among processing, microstructure and high temperature behaviour.
Orozco-Caballero, A., Carreño, Fernando
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Yuanzineng kexue jishu, 2023 ASME 2021 code provides constitutive equation for high temperature creep of 316H stainless steel. The paper aims to help engineers and researchers correctly evaluate the strain and creep damage of high-temperature equipment by using the equation. Firstly,
LI Zhi;MO Yafei;GAO Fuhai;ZENG Xiaojia;ZHAO Shouzhi
doaj
Subroutine Embedding and Finite Element Simulation of the Improved Constitutive Equation for Ti6Al4V during High-Speed Machining. [PDF]
Materials (Basel), 2023 Liu L, Wu W, Zhao Y, Cheng Y.
europepmc +1 more source