Results 41 to 50 of about 216,858 (244)
Constitutive equation of butter at static loading
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2008 This study focuses on the constitutive modelling of finite deformation in the commercially obtained butter (composition is 83 % of milk fat) at the temperature 17–20 °C.
Šárka Nedomová, Libor Severa
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Constitutive modeling of Ti-2.7Cu alloy based on strain compensation and PSO-BP neural network
Cailiao gongcheng, 2019 The isothermal compression tests of Ti-2.7Cu alloy were tested to study the hot deformation behavior in temperature range of 740-890℃ and strain rate range of 0.001-10s-1 on a Gleeble-3500 thermomechanical simulator.
WAN Peng +4 more
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Modelling, identification and application of phenomenological constitutive laws over a large strain rate and temperature range [PDF]
, 2013 A review of the different phenomenological thermo-viscoplastic constitutive models often applied to forging and machining processes is presented. Several of the most common models have been identified using a large experimental database (Hor et al., 2013)
GERMAIN, Guénaël +3 more
core +8 more sources
Colloquium: Mechanical formalisms for tissue dynamics
, 2015 The understanding of morphogenesis in living organisms has been renewed by tremendous progressin experimental techniques that provide access to cell-scale, quantitative information both on theshapes of cells within tissues and on the genes being ...
A. Desmaison +102 more
core +6 more sources
Journal of Materials Research and Technology, 2021 The application of appropriate constitutive equation describing the relationship between the flow stress, temperature and strain rate is essential to get deep insight into the process mechanism of friction stir welding (FSW).
Chunliang Yang, ChuanSong Wu, Song Gao
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source