Results 61 to 70 of about 216,858 (244)

Physics-Based Constitutive Model to Predict Dynamic Recovery Behavior of BFe10-1-2 Cupronickel Alloy during Hot Working

open access: yesHigh Temperature Materials and Processes, 2016
The hot deformation behavior of BFe10-1-2 cupronickel alloy was investigated over wide ranges of deformation temperature and strain rate. The physics-based constitutive model was developed to predict the dynamic recovery (DRV) behavior of BFe10-1-2 ...
Cai Jun   +3 more
doaj   +1 more source

High temperature flow behavior and constitutive model of 35CrMo steel

open access: yesJournal of Hebei University of Science and Technology, 2019
In order to describe the stress-strain relationship of 35CrMo steel and establish constitutive model of material, the high temperature thermal simulation compression experiment of hot rolled 35CrMo steel is conducted by the Gleeble3800 thermal simulation
Xilei HU   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Determination of Johnson–Cook Constitutive Parameters for Cutting Simulations

open access: yesMetals, 2019
The Johnson–Cook constitutive equation is very widely used for simulating cutting processes. Different methods are applied for establishing parameters of the constitutive equation.
Michael Storchak   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Combined creep and plastic analysis with numerical methods [PDF]

open access: yes, 2013
The combination of plastic and creep analysis formulation are developed in this paper. The boundary element method and the finite element method are applied in plates in order to do the numerical analysis.
Kryvko, A.   +2 more
core  

Modeling the initial mechanical response and yielding behavior of gelled crude oil

open access: yesOpen Physics, 2018
The initial mechanical response and yielding behavior of gelled crude oil under constant shear rate conditions were investigated. By putting the Maxwell mechanical analog and a special dashpot in parallel, a quasi-Jeffreys model was obtained. The kinetic
Lei Chen   +4 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Microforces and the Theory of Solute Transport

open access: yes, 1999
A generalized continuum framework for the theory of solute transport in fluids is proposed and systematically developed. This framework rests on the introduction of a generic force balance for the solute, a balance distinct from the macroscopic momentum ...
Fried, Eliot, Sellers, Shaun
core   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

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