Results 41 to 50 of about 24,902,874 (336)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Validation of a damage constitutive model based on logistic model dedicated to the mechanical behavior of the rock

Geomechanics and Geophysics for Geo-Energy and Geo-Resources
The establishment of mechanical models of rocks can provide crucial guidance to the surrounding rocks stability analysis in the rock engineering. According to statistical damage theory and Mohr–Coulomb strength criterion, the Logistic model is used to ...
Kai Chen, Roberto Cudmani, Andres Alfonso Pena Olarte   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Numerical derivation of constitutive models for unbonded flexible risers [PDF]

, 2009
This is the post-print version of the final paper published in International Journal of Mechanical Sciences. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections,
Alfano, G, Bahai, H, Bahtui, A
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Nonlinear Statistical Damage Constitutive Model for Porous Rocks

Advances in Civil Engineering, 2020
In the current paper, the deformation behaviours of rocks during compression are studied by testing 10 groups of sandstone samples with different porosity characteristics.
Yue Pan, Zhiming Zhao, Liu He, Guang Wu
doaj   +1 more source

Development and Application of High-Temperature Constitutive Model of HNi55-7-4-2 Alloy

Metals, 2020
The constitutive model is still not available for theoretical and engineering analysis of HNi55-7-4-2 alloy, which is a new type of wear-resistant brass alloy widely applied to car synchronizer rings and ship condenser tubes etc.
Qiang Liang, Xin Liu, Ping Li, Ping Ding, Xianming Zhang   +4 more
doaj   +1 more source

Effects of the Unified Viscoplastic Formulation and Temperature Terms on the Thermomechanical Behavior of Soldering Materials [PDF]

, 2012
Solder materials are critical packaging compounds and due to usually weakest melting temperature among packaging constitutive materials, thus, they are frequently subjected to a multitude of physical phenomena: creep, fatigue and combined hardening ...
Alexis, Joël, Dalverny, Olivier, Karama, Moussa, Msolli, Sabeur   +3 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Correction of Flow Curves and Constitutive Modelling of a Ti-6Al-4V Alloy

Metals, 2018
Isothermal uniaxial compressions of a Ti-6Al-4V alloy were carried out in the temperature range of 800–1050 °C and strain rate range of 0.001–1 s−1. The effects of friction between the specimen and anvils as well as the increase in temperature caused by ...
Ming Hu, Limin Dong, Zhiqiang Zhang, Xiaofei Lei, Rui Yang, Yuhui Sha   +5 more
doaj   +1 more source