FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
FUsion-based ConstitutivE model (FuCe): Towards model-data augmentation in constitutive modelling
CoRRConstitutive modelling is crucial for engineering design and simulations to accurately describe material behavior. However, traditional phenomenological models often struggle to capture the complexities of real materials under varying stress conditions due to their fixed forms and limited parameters.
Tushar, Sawan Kumar, Souvik Chakraborty
openaire +2 more sources
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
KONA Powder and Particle Journal, 2014 Die compaction of powders is a process which involves filling a die with powder, compression of the powder using rigid punches to form a dense compact, and ejection from the die.
Csaba Sinka
doaj +1 more source
The Managerial Constitution: The Convergence of Constitutional and Corporate Governance Models
SSRN Electronic Journal, 2013 This paper proposes the concept of the “Managerial Constitution”, which advocates the convergence between constitutional and corporate governance models. Such concept is based on the interpretation of certain features of the Brazilian Constitution enacted in 1988 that may serve as a model for modern democracies in developing countries.
openaire +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Microstructure Evolution, Constitutive Modelling, and Superplastic Forming of Experimental 6XXX-Type Alloys Processed with Different Thermomechanical Treatments. [PDF]
Materials (Basel), 2023 Mochugovskiy AG +5 more
europepmc +1 more source
A constitutive model for analyzing martensite formation in austenitic steels deforming at high strain rates [PDF]
, 2012 This study presents a constitutive model for steels exhibiting SIMT, based on previous seminal works, and the corresponding methodology to estimate their parameters.
FERNANDEZ-SAEZ, José +5 more
core +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Constitutive Modelling of Polylactic Acid at Large Deformation Using Multiaxial Strains. [PDF]
Polymers (Basel), 2021 Sweeney J +4 more
europepmc +1 more source