Results 91 to 100 of about 200,600 (296)
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Ambiguity in a Dialectical Perspective
The distinction between constitutive and regulative rules is applied to rules for critical discussion that have to do with the use of ambiguous expressions.
Jan Albert van Laar
doaj +1 more source
CONSTITUTION AS A STIMULATION FACTOR OF CONSTRUCTION SOCIOCULTURAL CAPITAL
In all areas of society, it is necessary to actively and continuously act on unique (constitutive) rules that apply equally to all and perform non-selective and unprivileged regulation, coordination, organization and limitation of human behavior.
Nikša Grgurević, Saša Mitrić
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Towards the Emergence of Constitutive Rules for Equitable Agribusiness Value Chains [PDF]
Replaced with revised version of paper 10/18/07.Agribusiness,
Bourgeois, Robin
core +1 more source
Instituted or Embedded? Legal, Fiscal and Economic Institutionalisation of Markets [PDF]
Recent debates in economic sociology have raised questions about the significance of law in the economy, and specifically the role of law in the operation of markets.
Harvey, M
core
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Does Ontogenesis of Social Ontology Start with Pretence?
Rakoczy and Tomasello follow Searle in claiming that rule games need status function assignment and constitutive rules. But, in the case of pretend play, it is not easy to put together these notions with the natural world knowledge necessary to engage in
Gaetano Albergo
doaj +1 more source
Mimetic Constitutive Rules [PDF]
This paper deals with the question of how constitutive rules in Searle’s sense can be subject to definite constraints, or boundaries. Three kinds of boundaries to institutional constitution are here identified: ontological, structural, and pragmatic. All these kinds of boundaries to some extent depend on the context of the broader social practice for ...
openaire +3 more sources

