Results 71 to 80 of about 16,380 (285)
Commanding and Defining. On Eugenio Bulygin’s Theory of Legal Power-Conferring Rules
Crítica, 2017 This paper aims to explore two objections raised against Bulygin’s second approach to the definition of the nature of legal power-conferring rules. According to the first objection, such an account is vague about what is defined by legal power-conferring
Gonzalo Villa Rosas
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 2010 Context has always been central to Searle’s account of constitutive rules, as can be appreciated from his classic formulation, “X counts as Y in context C.” But while the nature of X and Y in Searle have been widely discussed, the role of the context in ...
ROVERSI, CORRADO
core
Rule of law and constitutional democracy
Milletleraras, 2015 The rule of law is a traditional concept much used but little examined in its current magnitude. It is a cornerstone of contemporary constitutional democracy as underscored by its paramount role in cementing all of the transitions from authoritarian or totalitarian regimes to constitutional democracy. Moreover, rule of law is one of the three essential
openaire +3 more sources
Constitutive rules of precedent
Revus, 2022 The purpose of this paper is to reject the thesis that a system of precedent is established with a prescriptive norm. This claim is supported by two lines of reasoning. First, it is claimed that systems of precedent necessarily require constitutive norms and not prescriptive norms.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ambiguity in a Dialectical Perspective
Informal Logic, 2001 The distinction between constitutive and regulative rules is applied to rules for critical discussion that have to do with the use of ambiguous expressions.
Jan Albert van Laar
doaj +1 more source
CONSTITUTION AS A STIMULATION FACTOR OF CONSTRUCTION SOCIOCULTURAL CAPITAL
STED Journal, 2021 In all areas of society, it is necessary to actively and continuously act on unique (constitutive) rules that apply equally to all and perform non-selective and unprivileged regulation, coordination, organization and limitation of human behavior.
Nikša Grgurević, Saša Mitrić
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Modelling of dynamic damage and failure in aluminium alloys [PDF]
, 2012 A physically based damage and failure model, applicable to orthotropic metals is proposed in this paper. To account for the physical mechanisms of failure, the concept of thermally activated damage initially proposed by Klepaczko [1], has been adopted as
Djordjevic, Nenad +3 more
core +1 more source