Results 51 to 60 of about 200,600 (296)

Internal goods to legal practice: reclaiming fuller with macintyre [PDF]

open access: yes, 2015
Lon Fuller rejected legal positivism because he believed that the ‘procedural morality of law’ established a necessary connection between law and morals. Underpinning his argument is a claim that law is a purposive activity grounded by a relationship of
Retter, Mark
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A thermoviscoelastic finite deformation constitutive model based on dual relaxation mechanisms for amorphous shape memory polymers

open access: yesInternational Journal of Smart and Nano Materials, 2023
This paper proposes a new thermoviscoelastic finite deformation model incorporating dual relaxation mechanisms to predict the complete thermo-mechanical response of amorphous shape memory polymers.
Hao Duan   +4 more
doaj   +1 more source

Constitutional Amendment Rules

open access: yesSSRN Electronic Journal, 2011
The difficulty of constitutional amendment, in most contexts, clearly depends on both the formal rules governing amendment and a variety of other factors. This chapter explores the significance one such non-textual factor: the size, or scale, of a polity.
Dixon, Rosalind, Holden, Richard T.
openaire   +2 more sources

Some consequences of stress range dependent constitutive models in creep [PDF]

open access: yes, 2010
Studies of the behaviour of structural components at high temperature subject to creep have a long history and their behavioural characteristics, certainly for constant and cyclic load, well established.
Boyle, James
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Fractional-Order Elastoplastic Modeling of Sands Considering Cyclic Mobility

open access: yesJournal of Marine Science and Engineering, 2021
Seabed soil may experience a reduction in strength or even liquefaction when subjected to cyclic loadings exerted by offshore structures and environmental loadings such as ocean waves and earthquakes.
Leiye Wu, Wei Cheng, Zhehao Zhu
doaj   +1 more source

Here is the author! Hyperlinks as constitutive rules of hypertextual communication [PDF]

open access: yes, 2017
In this paper, we examine the importance of hyperlinks in revealing the presence of the hypertext author and his decisive role in defining and controlling the dialogue with the user/reader through the hypertext.
Mazzali-Lurati, Sabrina
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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