Results 51 to 60 of about 1,378,662 (232)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Mechanics of Constitutive Modeling
, 2005 Constitutive modeling is the most intensive research field within solid mechanics. This work offers a comprehensive, parallel treatment of constitutive models and appropriate numerical solution strategies, at a conceptual level and with discussion of ...
Ottosen, Niels Saabye. +3 more
core +1 more source
Modelling, identification and application of phenomenological constitutive laws over a large strain rate and temperature range [PDF]
, 2013 A review of the different phenomenological thermo-viscoplastic constitutive models often applied to forging and machining processes is presented. Several of the most common models have been identified using a large experimental database (Hor et al., 2013)
GERMAIN, Guénaël +3 more
core +1 more source
On the formation of linguistic constructivism from Austin to Searle
Семиотические исследованияThe article examines the evolution of speech act theory, one of the key ideas of ordinary language philosophy in the twentieth century. The research problem lies in the indeterminacy of the methodological relationship between the concepts of John Austin ...
Svetlana S. Chistanova
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Human Research in Rehabilitation, 2011 In this paper the author considers the rules of sports (constitutive and sportsmanship rules), moral values of sports (justice, honesty, responsibility, benefi cence) and fair play.
Željko Kaluđerović
doaj +1 more source
Constitutive Laws of Viscoplasticity in Dynamic Response of Structures
Engineering Transactions, 2015 The aim of the paper is to discuss the differences which appear in elasto-viscoplastic dynamic analysis of structures using different types of constitutive equations.
K. Woźnica, P. Kłosowski
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Commanding and Defining. On Eugenio Bulygin’s Theory of Legal Power-Conferring Rules
Crítica, 2017 This paper aims to explore two objections raised against Bulygin’s second approach to the definition of the nature of legal power-conferring rules. According to the first objection, such an account is vague about what is defined by legal power-conferring
Gonzalo Villa Rosas
doaj