Results 51 to 60 of about 16,380 (285)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Study on Dynamic Constitutive Model of Weakly Consolidated Soft Rock in Western China
Shock and Vibration, 2020 To obtain the impact mechanical response and establish the dynamic damage constitutive relationship of frozen sandstone at low temperature conditions, the impact test of Cretaceous red sandstone under different temperatures was conducted using a split ...
Lei Wang +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Challenging the constitutive rules inviolability dogma [PDF]
, 2012 According to Searle (1969) a constitutive rule creates the very possibility of the entity it rules. Later on, other scholars - such as Benoist (2003), Conte (1983), Guastini (1983) - pointed out the inviolability of constitutive rules.
U. Sconfienza +3 more
core
Constitutive modelling and mechanical characterization of aluminium-based metal matrix composites produced by spark plasma sintering [PDF]
, 2010 Spark plasma sintering has been applied to the production of aluminium-based functionally graded material systems to be used in abrasive and high temperature conditions.
Estournès, Claude +6 more
core +1 more source
John Searle on Institutional Facts
Metaphysics, 2010 One general categorization by some of the contemporary analytic philosophers divides the facts into institutional and brute. The characteristic of institutional facts is that they are constituted by collective recognition.
M.A. Abdullahi, M.T. Janmohammadi
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Damage constitutive model of jointed rock mass considering structural features and load effect
Reviews on Advanced Materials Science, 2023 Rock masses in underground engineering are usually damaged, which are caused by rock genesis and environmental stress. Studying the constitutive relationship between rock strength and deformation under loading is crucial for the design and evaluation of ...
Sun Bing +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source