Results 41 to 50 of about 1,378,662 (232)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Six Heresies on Constitutive Rules [PDF]
, 2019 The concept of “constitutive rule” is inextricably linked with the philosophy of John R. Searle and with the field of study that we now call “social ontology”, a domain that owes much to Searle’s work.
Roversi, Corrado
core +1 more source
International Journal of Smart and Nano Materials, 2023 This paper proposes a new thermoviscoelastic finite deformation model incorporating dual relaxation mechanisms to predict the complete thermo-mechanical response of amorphous shape memory polymers.
Hao Duan +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
John Searle on Institutional Facts
Metaphysics, 2010 One general categorization by some of the contemporary analytic philosophers divides the facts into institutional and brute. The characteristic of institutional facts is that they are constituted by collective recognition.
M.A. Abdullahi, M.T. Janmohammadi
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Lack of correlation between constitutive and induced resistance to a herbivore in crucifer plants: real or flawed by experimental methods? [PDF]
, 2009 The correlation between constitutive and induced resistance to herbivores in plants has long been of interest to evolutionary biologists, and various approaches to determining levels of resistance have been used in this field of research.
Dicke, M. +4 more
core +1 more source
Study on Dynamic Constitutive Model of Weakly Consolidated Soft Rock in Western China
Shock and Vibration, 2020 To obtain the impact mechanical response and establish the dynamic damage constitutive relationship of frozen sandstone at low temperature conditions, the impact test of Cretaceous red sandstone under different temperatures was conducted using a split ...
Lei Wang +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source