Results 151 to 160 of about 13,265,536 (249)

Automatic therapy planning based on concept drift. [PDF]

open access: yesFront Rehabil Sci
Ramírez-Cruz M   +3 more
europepmc   +1 more source

Prediction of Prion Proteins in E. coli Based on Bimodal Sequence Characteristics

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prions are infectious proteins that bear misfolded conformations capable of converting folded states into misfolded aggregates under physiologically relevant conditions. In mammals, prions cause deadly maladies including Creutzfeldt‐Jakob and chronic wasting disease. To date, several prion proteins have been identified in eukaryotes, primarily
Katherine Shreeve   +5 more
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Impact of Packaging and Recycling Systems on Material Recirculation: A Stage‐Decomposition Model

open access: yesPackaging Technology and Science, EarlyView.
A system‐level view emerges from decomposing recycling into four stages (participation, collection, sorting and process yield), diagnosing constraints and targeting interventions. Cumulative equivalent uses (CEUs) quantify long‐term retention, revealing marginal improvements at high baselines generate disproportionately larger gains than low‐baseline ...
Diogo Figueirinhas   +3 more
wiley   +1 more source

Integrating Image Segmentation and Deep Learning to Improve Radio Frequency Propagation Models

open access: yesInternational Journal of Satellite Communications and Networking, EarlyView.
ABSTRACT This paper proposes a multi‐sensor approach to improve radio frequency (RF) propagation models, which play a key role in the rapidly expanding field of connected vehicle technology. Focusing on the 1‐ to 20‐GHz frequency range, which is critical for both satellite‐to‐vehicle and base station‐to‐vehicle communications, our study introduces a ...
Jonathan Israel   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy