Results 41 to 50 of about 610,742 (235)

A penalty method for PDE-constrained optimization in inverse problems

, 2015
Many inverse and parameter estimation problems can be written as PDE-constrained optimization problems. The goal, then, is to infer the parameters, typically coefficients of the PDE, from partial measurements of the solutions of the PDE for several right-
Herrmann, Felix J., van Leeuwen, Tristan
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

CIOA: Circle-Inspired Optimization Algorithm, an algorithm for engineering optimization

SoftwareX, 2022
This paper presents a new, robust and very efficient metaheuristic optimization algorithm, called Circle Inspired Optimization Algorithm (CIOA), for solving constrained and unconstrained engineering optimization problems. The inspiration for the proposed
Otávio Augusto Peter de Souza, Letícia Fleck Fadel Miguel   +1 more
doaj   +1 more source

Exploiting symmetries in SDP-relaxations for polynomial optimization

, 2012
In this paper we study various approaches for exploiting symmetries in polynomial optimization problems within the framework of semi definite programming relaxations.
Barvinok AI, Barvinok AI, Bröcker L, Cordian Riener, Dixon JD, Henrion D, James G, Jean B. Lasserre, Lasserre JB, Lina Jansson Andrén, Serre J-P, The GAP Group, Thorsten Theobald   +12 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Constrained Bayesian Optimization: A Review

IEEE Access
Bayesian optimization is a sequential optimization method that is particularly well suited for problems with limited computational budgets involving expensive and non-convex black-box functions.
Sasan Amini, Inneke Vannieuwenhuyse, Alejandro Morales-Hernandez   +2 more
doaj   +1 more source

Active Exploration by Chance-Constrained Optimization for Voltage Regulation with Reinforcement Learning

Energies, 2022
Voltage regulation in distribution networks encounters a challenge of handling uncertainties caused by the high penetration of photovoltaics (PV). This research proposes an active exploration (AE) method based on reinforcement learning (RL) to respond to
Zhenhuan Ding, Xiaoge Huang, Zhao Liu
doaj   +1 more source

Computer program for parameter optimization [PDF]

, 1968
Flexible, large scale digital computer program was designed for the solution of a wide range of multivariable parameter optimization problems.
Glatt, C. R., Hague, D. S.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Constrained Optimization of MIMO Training Sequences

EURASIP Journal on Advances in Signal Processing, 2007
Multiple-input multiple-output (MIMO) systems have shown a huge potential for increased spectral efficiency and throughput. With an increasing number of transmitting antennas comes the burden of providing training for channel estimation for coherent ...
Coon Justin P, Sandell Magnus
doaj   +2 more sources