Results 41 to 50 of about 616,628 (303)
Progressive construction of a parametric reduced-order model for PDE-constrained optimization [PDF]
, 2014 An adaptive approach to using reduced-order models as surrogates in PDE-constrained optimization is introduced that breaks the traditional offline-online framework of model order reduction.
Farhat, Charbel, Zahr, Matthew J.
core
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hybrid Stochastic Ranking for Constrained Optimization
IEEE Access, 2020 Teaching learning based optimization (TLBO) algorithm is a distinguished nature-inspired population-based meta-heuristic, which is basically designed for unconstrained optimization.
Muhammad Asif Jan +7 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
A Method for Balancing Provider Schedules in Outpatient Specialty Clinics
MDM Policy & Practice, 2020 Background. Variability in outpatient specialty clinic schedules contributes to numerous adverse effects including chaotic clinic settings, provider burnout, increased patient waiting times, and inefficient use of resources.
Bjorn P. Berg +3 more
doaj +1 more source
A penalty method for PDE-constrained optimization in inverse problems
, 2015 Many inverse and parameter estimation problems can be written as PDE-constrained optimization problems. The goal, then, is to infer the parameters, typically coefficients of the PDE, from partial measurements of the solutions of the PDE for several right-
Herrmann, Felix J., van Leeuwen, Tristan
core +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Investigation of the iCC Framework Performance for Solving Constrained LSGO Problems
Algorithms, 2020 Many modern real-valued optimization tasks use “black-box” (BB) models for evaluating objective functions and they are high-dimensional and constrained.
Alexey Vakhnin, Evgenii Sopov
doaj +1 more source
Improved Whale Optimization Algorithm for Solving Constrained Optimization Problems
Discrete Dynamics in Nature and Society, 2021 In view of the shortcomings of the whale optimization algorithm (WOA), such as slow convergence speed, low accuracy, and easy to fall into local optimum, an improved whale optimization algorithm (IWOA) is proposed.
Gui-Ying Ning, Dun-Qian Cao
doaj +1 more source