Results 31 to 40 of about 2,261 (257)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Reimagining academic identities in response to research demands at Universities of Technology
Critical Studies in Teaching and Learning, 2020 In the last volume of this journal, Garraway and Winberg called for a reimagination of Universities of Technology (UoT) within the South African higher education system.
Thobani Gumbi, Sioux McKenna
doaj +1 more source
On relaxing the Mangasarian–Fromovitz constraint qualification
Positivity, 2013 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kruger, Alexander Y. +2 more
openaire +3 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Journal of Mathematical Extension, 2013 In this paper, we consider the Abadie and the Basic constraint qualifications (CQ) for lower level problem of convex generalized semi-infinite programming problems, and we derive the Fritz-John necessary optimality conditions for the problem under ...
N. Kanzi
doaj
Optimality and Constraint Qualifications in Vector Optimization [PDF]
, 2010 We propose a unifying approach in deriving constraint qualifications and theorem of the alternative. We first introduce a separation theorem between a subspace and the non-positive orthant, and then we use it to derive a new constraint qualification for a smooth vector optimization problem with inequality constraints.
MARTEIN, LAURA, CAROSI, LAURA
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
On the uniqueness of the optimal solution in linear programming
Journal of Numerical Analysis and Approximation Theory, 2006 In this paper numerous necessary and sufficient conditions will be given for a vector to be the unique optimal solution of the primal problem, as well as for that of the dual problem, and even for the case when the primal and the dual problem have unique
Peter Szilágyi
doaj +2 more sources