Results 101 to 110 of about 2,249,985 (314)

Constructing Constraints

open access: yes, 1998
It is well-known that there is a trade-off between the expressive power of a constraint language and the tractability of the problems it can express. But how can you determine the expressive power of a given constraint language, and how can you tell if problems expressed in that language are tractable?
openaire   +3 more sources

Internal financial constraints, external financial constraints, and investment choice: Evidence from a panel of UK firms [PDF]

open access: yes
This paper uses a panel of 24184 UK firms over the period 1993-2003 to study the extent to which the sensitivity of investment to cash flow differs at firms facing different levels of internal and external financial constraints.
Alessandra Guariglia
core  

Literature review for the topic of automation of scheduling classes and exams in higher education institutions

open access: yesAdvanced Engineering Research, 2017
Introduction. Schedules of classes and exams are crucial components in the training process organization. Their quality directly affects the successful mastering of learning materials and ensures physical and psychological health of the educational ...
Wadhah M Al-Gabri
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Symbolic Constraints in Constructive Geometric Constraint Solving

open access: yesJournal of Symbolic Computation, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Christoph M. Hoffmann   +1 more
openaire   +3 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Measuring firms’ financial constraints: Evidence for Portugal through different approaches [PDF]

open access: yes
Today's shortage of financial resources calls for the attention of researchers to the problem of financial constraints faced by firms. In this paper we analyse firms' financial constraints by estimating both investment-cash flow sensitivities and cash ...
Filipe Silva, Carlos Carreira
core  

The Xed out construction: between productivity and creativity

open access: yesQuaderns de Filologia: Estudis Lingüístics, 2014
The Xed out  construction, as in I’m all coffeed out , is said to be completely productive. This paper argues that unrestrained productivity is more the exception than the rule.
Vincent Hugou
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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