Results 101 to 110 of about 5,329,946 (348)

Ghost Constraints on Modified Gravity

, 2004
We show that general infrared modifications of the Einstein-Hilbert action obtained by addition of curvature invariants are not viable. These modifications contain either ghosts or light gravity scalars.
Alvaro Núñez, Barrow, Carroll, Carroll, Deffayet, Dick, Dolgov, Dvali, Dvali, Dvali, Dvali, Flanagan, Kalara, Meng, Nicolis, Nojiri, Núñez, Perlmutter, Riess, Slava Solganik, Tonry, Van Nieuwenhuizen, Van Nieuwenhuizen, Vollick   +23 more
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CLASSICAL DESCRIPTIONS OF THE GEOMETRODYNAMICS OF CHARGED BLACK HOLES

Odessa Astronomical Publications, 2019
Analytical aspects of the classical geometrodynamics of charged black holes are considered. The classical model of the charged BHs is the spherically symmetric configuration of the electromagnetic and gravitational fields in GR.
V. D. Gladush
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

The New Butterfly Relaxation Method for Mathematical Programs with Complementarity Constraints

, 2021
Jean‐Pierre Dussault, Mounir Haddou, Tangi Migot   +2 more
openalex   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Addressing Dependent Data in Constrained Optimization Problems: A WOA-based Algorithm [PDF]

International Journal of Industrial Electronics, Control and Optimization
Optimization algorithms are widely used in various fields to find the best solution to a problem by minimizing or maximizing an objective function, subject to certain constraints.
Asieh Ghanbarpour, Soheil Zaremotlagh, Fahimeh Dabaghi-Zarandi   +2 more
doaj   +1 more source

Superselection from canonical constraints

, 2004
The evolution of both quantum and classical ensembles may be described via the probability density P on configuration space, its canonical conjugate S, and an_ensemble_ Hamiltonian H[P,S]. For quantum ensembles this evolution is, of course, equivalent to
Dirac P A M, Elze H-T, Galindo A, Goldstein H, Hall M J W, Hall M J W, Henneaux M, Mehrafarin M, Roman P, Weinberg S, Zakharov V E   +10 more
core   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source