Results 91 to 100 of about 1,744,639 (315)

Addressing Dependent Data in Constrained Optimization Problems: A WOA-based Algorithm [PDF]

open access: yesInternational Journal of Industrial Electronics, Control and Optimization
Optimization algorithms are widely used in various fields to find the best solution to a problem by minimizing or maximizing an objective function, subject to certain constraints.
Asieh Ghanbarpour   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Borrowing Constraints, Portfolio Choice, and Precautionary [PDF]

open access: yes
This paper studies effects of two classes of borrowing constraints, collateral- and income-based, on wealth accumulation, portfolio behavior and on precautionary motives.
Christis Hassapis, Michael Haliassos
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Financial constraints, exports and monetary integration - Financial constraints and exports: An analysis of Portuguese firms during the European monetary integration [PDF]

open access: yes
Financial constraints are a key determinant that hinders firms' ability to export. This paper analyses the nexus between these constraints and firms' engagement in international trade, as well as it explores the impact of the European monetary ...
Filipe Silva, Carlos Carreira
core  

Control over the deployment of an orbital tether system of great length

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2017
Control of deploying an extended tether system into the vertical position is considered in the paper. It is assumed that in the initial state the system consisting of two space vehicles moves in a circular Earth orbit. We propose nominal control programs
Ch. Wang, Yu. M. Zabolotnov
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Emptiness and desire in the first rule of logic

open access: yesSign Systems Studies, 2018
Charles Sanders Peirce’s first rule of logic (EP 2.48, 1898) identifies the inception point of human inquiry. Taking a closer look at this principle, we find at its core a necessary relationship between emptiness and desire that underlies all genuine ...
Jamin Pelkey
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Financing Constraints and Entrepreneurship [PDF]

open access: yes
Financing constraints are one of the biggest concerns impacting potential entrepreneurs around the world. Given the important role that entrepreneurship is believed to play in the process of economic growth, alleviating financing constraints for would-be
William Kerr, Ramana Nanda
core  

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