Potential thresholds of critically increased cardiac-related spinal cord motion in degenerative cervical myelopathy. [PDF]
INTRODUCTION: New diagnostic techniques are a substantial research focus in degenerative cervical myelopathy (DCM). This cross-sectional study determined the significance of cardiac-related spinal cord motion and the extent of spinal stenosis as ...
Pfender N+16 more
europepmc +6 more sources
Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission. [PDF]
Inhibitory GABA-ergic neurotransmission is fundamental for the adult vertebrate central nervous system and requires low chloride concentration in neurons, maintained by KCC2, a neuroprotective ion transporter that extrudes intracellular neuronal chloride.
Bortsov, Andrey+13 more
core +1 more source
Accurate preoperative diagnosis of pericardial constriction using cine computed tomography [PDF]
Objectives. The purpose of this study was to determine the accuracy of cine computed tomography in the diagnosis of constrictive pericarditis.Background.
Grover-McKay, Maleah+3 more
core +1 more source
On the Role of Mechanics in Chronic Lung Disease. [PDF]
Progressive airflow obstruction is a classical hallmark of chronic lung disease, affecting more than one fourth of the adult population. As the disease progresses, the inner layer of the airway wall grows, folds inwards, and narrows the lumen.
Eskandari, Mona+2 more
core +3 more sources
Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]
Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core +1 more source
Can Bandl’s ring be recurrent? [PDF]
Background: Bandl’s ring is a pathologic contraction ring of the uterus that is associated with obstructed labor. Case: A 35-year-old with an uncomplicated past medical history was found to have a Bandl’s ring in her first pregnancy during a cesarean ...
Maassen, Rachel A, Shirazi, Elizabeth M
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An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. [PDF]
Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma.
Abagyan, Ruben+9 more
core +3 more sources
Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. [PDF]
Thrombospondins (Thbs) are a family of five secreted matricellular glycoproteins in vertebrates that broadly affect cell-matrix interaction. While Thbs4 is known to protect striated muscle from disease by enhancing sarcolemmal stability through increased
Brody, Matthew J+11 more
core +3 more sources
Evaluation of Immunomodulatory Biomarkers in a Pressure Overload Model of Heart Failure [PDF]
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90380/1/phco.27.4.504 ...
Barry E Bleske+7 more
core +2 more sources
Calpains as Potential Therapeutic Targets for Myocardial Hypertrophy [PDF]
Calpain; Calpastatin; Myocardial hypertrophyCalpaína; Calpastatina; Hipertrofia miocárdicaCalpaïna; Calpastatina; Hipertròfia miocàrdicaDespite advances in its treatment, heart failure remains a major cause of morbidity and mortality, evidencing an ...
Aluja Gonzalez, David+4 more
core +1 more source