Results 11 to 20 of about 13,489 (314)

Preductal Segmental Tubular Aortic Hypoplasia in Perinatally Died Stabyhoun Puppies [PDF]

Animals, 2023
Background: A high perinatal mortality rate in the Stabyhoun breed prompted one of the Dutch breeding organizations to start an investigation. Preductal segmental tubular aortic hypoplasia is an extremely rarely documented congenital vascular anomaly in ...
Marie D. B. van Staveren, Guy C. M. Grinwis, Marjolein L. den Toom, Viktor Szatmári   +3 more
doaj   +5 more sources

The Role of Magnesium in the Management of Cerebral Vasospasm [PDF]

Neurology Research International, 2013
Subarachnoid hemorrhage (SAH) is characterized by bleeding into the subarachnoid space, often caused by ruptured aneurysm. Aneurysmal rupture occurs in 700,000 individuals per year worldwide, with 40,000 cases taking place in the United States.
Mitchell J. Odom, Scott L. Zuckerman, J Mocco   +2 more
doaj   +2 more sources

Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy [PDF]

Frontiers in Physiology, 2018
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Wenbin Gao, Wenbin Gao, Wenbin Gao, Zheng Zhou, Zheng Zhou, Zheng Zhou, Birong Liang, Birong Liang, Birong Liang, Yusheng Huang, Yusheng Huang, Yusheng Huang, Zhongqi Yang, Zhongqi Yang, Zhongqi Yang, Yang Chen, Yang Chen, Lu Zhang, Lu Zhang, Lu Zhang, Cui Yan, Cui Yan, Cui Yan, Jiajia Wang, Jiajia Wang, Jiajia Wang, Lu Lu, Lu Lu, Lu Lu, Zhaorui Wen, Zhaorui Wen, Shaoxiang Xian, Shaoxiang Xian, Shaoxiang Xian, Lingjun Wang, Lingjun Wang, Lingjun Wang   +36 more
doaj   +3 more sources

Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure [PDF]

, 2022
BACKGROUND: Abnormalities in cardiac energy metabolism occur in heart failure (HF) and contribute to contractile dysfunction, but their role, if any, in HF-related pathologic remodeling is much less established.
Dey, Swati, Yanek, Lisa, Agrimi, Jacopo, Lai, Shenghan, O'Rourke, Brian, Zhang, Yi, Paolocci, Nazareno, Weiss, Robert G., Steenbergen, Charles, Gabr, Refaat, Keceli, Gizem, Schär, Michael, Sourdon, Joevin, Bottomley, Paul, Gupta, Ashish, Bottomley, Paul A., Tocchetti, Carlo G., Weiss, Robert G, Yanek, Lisa R., Gerstenblith, Gary, Yanek, Lisa R, Tocchetti, Carlo G, Schaer, Michael, Weiss, Robert, Leppo, Michelle, Bottomley, Paul A, Wang, Yibin, Tocchetti, Carlo, Stuber, Annina, O’rourke, Brian   +29 more
core   +1 more source

Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart [PDF]

, 2021
The temporal nature of chromatin structural changes underpinning pathologic transcription are poorly understood. We measured chromatin accessibility and DNA methylation to study the contribution of chromatin remodeling at different stages of cardiac ...
Chapski D. J., Soehalim E., Rosa-Garrido M., Rosa-Garrido, Manuel, Chapski, Douglas J, Mason, Rosibel J., Mason, Rosibel J, Chapski, Douglas J., Ren S., Cabaj, Maximilian, Ren, Shuxun, Pellegrini M., Wang, Yibin, Wang Y., Soehalim, Elizabeth, Morselli, Marco, Cabaj M., Mason R. J., Vondriska T. M., Vondriska, Thomas M., Vondriska, Thomas M, Pellegrini, Matteo, Morselli M.   +22 more
core   +1 more source

Constrictive and Hypertrophic Strictures in Ileal Crohn's Disease [PDF]

, 2022
BACKGROUND & AIMS Strictures in Crohn's disease (CD) are classically attributed to fibromuscular hypertrophy of the intestinal wall. We have identified and characterized CD-related ileal strictures that result instead from mural constriction (ie ...
Colombel, Jean Frederic, Ellman, Jordan, Stocker, Daniel, Ko, Huaibin Mabel, Cho, Judy, Bhardwaj, Swati, Zhang, Xiaofei, Chen, Joyce, Hao, Yansheng, Taouli, Bachir, Liu, Qingqing, Liang, Yuanxin, Harpaz, Noam   +12 more
core   +1 more source

Endoscopic Balloon Dilation for Crohn’s Disease-Associated Strictures [PDF]

Clinical Endoscopy, 2017
Management of intestinal strictures associated with Crohn’s disease (CD) is clinically challenging despite advanced medical therapy directed toward mucosal healing to positively influence the natural course of CD-associated complications.
Thomas Klag, Jan Wehkamp, Martin Goetz
doaj   +1 more source

May-Thurner Syndrome, an Often Overlooked Cause of Deep Vein Thrombosis: A Case Report

Oman Medical Journal, 2021
Deep vein thrombosis (DVT) is a common medical condition, but the predisposing anatomical factors, which may be amenable to definitive treatment, are usually overlooked. Therefore, a high index of clinical suspicion is the key to early diagnosis.
Akhwand Shakeel Ahmad
doaj   +1 more source

Endoscopic management of anastomotic stricture after living-donor liver transplantation [PDF]

The Korean Journal of Internal Medicine, 2019
The most effective and fundamental treatment for end-stage liver disease is liver transplantation. Deceased-donor liver transplantation has been performed for many of these cases.
Dong Wook Lee, Jimin Han
doaj   +1 more source

Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure [PDF]

, 2021
BACKGROUND: Accumulating evidence suggests that the failing heart reprograms fuel metabolism toward increased utilization of ketone bodies and that increasing cardiac ketone delivery ameliorates cardiac dysfunction.
Yurista, Salva R, Nijholt, Kirsten T; id_orcid, Westenbrink, B Daan, Salva R. Yurista, John C. Newman, Matsuura, Timothy R, Nijholt, Kirsten T, McDaid, Kendra S, B. Daan Westenbrink, Verdin, Eric, Daniel P. Kelly, Kelly, Daniel P, Newman, John C, Leone, Teresa C, Rudolf A. de Boer, Herman H.W. Silljé, Westenbrink, B Daan; id_orcid, de Boer, Rudolf A, Kendra S. McDaid, Silljé, Herman H W, van Veldhuisen, Dirk J, Eric Verdin, Kirsten T. Nijholt, Teresa C. Leone, Swapnil V. Shewale, Dirk J. van Veldhuisen, Timothy R. Matsuura, Shewale, Swapnil V   +27 more
core   +1 more source