Results 111 to 120 of about 13,464 (314)

Tratamento da estenose umbilical em paciente com dermolipectomia vertical Treatment of the umbilical stenosis in a vertical dermolipectomy patient

Revista Brasileira de Cirurgia Plástica, 2011
INTRODUÇÃO: As alterações inestéticas da cicatriz umbilical em abdominoplastias verticais são frequentes fatores de insatisfação com os resultados. RELATO DE CASO: Apresentamos neste artigo um caso de estenose umbilical em paciente com dermolipectomia ...
André Luis Rosenhaim Monte
doaj   +1 more source

Assessment of peripheral vascular effects of antimigraine drugs in humans

, 1995
The vascular beds of the forearm and finger can be used to study the peripheral effects of antimigraine drugs under normal and pathologic circumstances. We have investigated the novel antimigraine drug sumatriptan, a selective agonist for 5HT1 receptors.
Camps, J., Chang, P. C., van Zwieten, P. A., Saxena, P. R., Bruning, T. A., Blauw, G. J., van Es, N. M., Ferrari, M. D.   +7 more
core   +1 more source

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Image_3_Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy.JPEG

, 2018
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Cui Yan (3820771), Zhongqi Yang (703895), Jiajia Wang (157207), Zheng Zhou (152309), Yusheng Huang (5780705), Birong Liang (5780702), Wenbin Gao (825538), Lingjun Wang (4516606), Zhaorui Wen (5780708), Yang Chen (9737), Lu Zhang (50563), Lu Lu (392), Shaoxiang Xian (4516615)   +12 more
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Inflammatory mechanisms and therapeutic targets in cerebral venous system diseases

Chinese Journal of Contemporary Neurology and Neurosurgery
Inflammation plays a crucial role in the pathogenesis, diagnosis, treatment monitoring and prognosis assessment of cerebral venous system diseases.
RUAN Yu‐shuang, DONG Zi‐kang, FANG Zhi, XIA Yuan‐peng   +3 more
doaj   +1 more source

Comprehensive Analysis of Lung Pathology in Soldiers Diagnosed with Constrictive Bronchiolitis [PDF]

C95. GROWING CANNABIS, FIGHTING FIRES, MILITARY DEPLOYMENT, AND INSTALLING COUNTERTOPS - THE OCCUPATIONAL RESPIRATORY THREATS OF THE 21ST CENTURY, 2020
S. Gutor, R.-H. Du, B.W. Richmond, S.V. Novitskiy, J.H. Newman, J.E. Loyd, R.F. Miller, T.S. Blackwell, V.V. Polosukhin   +8 more
openaire   +1 more source

Image_4_Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy.JPEG

, 2018
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Cui Yan (3820771), Zhongqi Yang (703895), Jiajia Wang (157207), Zheng Zhou (152309), Yusheng Huang (5780705), Birong Liang (5780702), Wenbin Gao (825538), Lingjun Wang (4516606), Zhaorui Wen (5780708), Yang Chen (9737), Lu Zhang (50563), Lu Lu (392), Shaoxiang Xian (4516615)   +12 more
core   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Amniotic band syndrome: the association between rare facial clefts and limb ring constrictions

, 1998
The pathologic cause of both rare craniofacial clefts and congenital limb ring constrictions is the subject of some debate. Uncommon though these two conditions are, they have often been anecdotally reported in association. This study sought to determine
Moore, M., Wallis, K., Coady, M.
core   +1 more source