Results 91 to 100 of about 1,422,521 (300)

Identification of differentially expressed genes and preliminary validations in cardiac pathological remodeling induced by transverse aortic constriction

International Journal of Molecular Medicine, 2019
Cardiac remodeling predisposes to heart failure if the burden is unresolved, and heart failure is an important cause of mortality in humans. The aim of the present study was to identify the key genes involved in cardiac pathological remodeling induced by pressure overload.
Wang, Hui-Bo, Huang, Rong, Yang, Kang, Xu, Man, Fan, Di, Liu, Ming-Xin, Huang, Si-Hui, Liu, Li-Bo, Wu, Hai-Ming, Tang, Qi-Zhu   +9 more
openaire   +3 more sources

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Reconstrução cirúrgica da estenose cicatricial de vias biliares pós-colecistectomia

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar uma série de casos de estenose cicatricial de vias biliares pós-colecistectomia submetidos à reconstrução cirúrgica. MÉTODOS: Foi realizado estudo retrospectivo de 27 pacientes submetidos à reconstrução cirúrgica da via biliar por ...
Aderivaldo Coelho de Andrade
doaj   +1 more source

A microfluidic platform for probing small artery structure and function.

Lab on a Chip, 2010
Although pathologic changes to the structure and function of small blood vessels are hallmarks of various cardiovascular diseases, limitations of conventional investigation methods (i.e.
A. Günther, S. Yasotharan, A. Vagaon, C. Lochovsky, S. Pinto, Jing-Li Yang, Calvin Lau, Julia Voigtlaender‐Bolz, S. Bolz   +8 more
semanticscholar   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Digitally Printed Eco‐Friendly Electronic Devices

Advanced Functional Materials, EarlyView.
Fabrication of electronics using eco‐friendly materials through digital printing routes is a promising strategy for improving life cycle sustainability and reducing the environmental impacts of conventional manufacturing. This review highlights state‐of‐the‐art eco‐friendly materials, green ink formulations, various resource‐efficient digital printing ...
Nitheesh M. Nair, Mikel Rincón‐Iglesias, Cristian Mendes‐Felipe, Fatemeh Etehadi, Senentxu Lanceros‐Méndez, Gerardo Hernandez‐Sosa   +5 more
wiley   +1 more source

Simultaneous Adrenal and Cardiac GPCR-Gβγ Inhibition Halts Heart Failure Progression

Journal of the American College of Cardiology, 2014
Objective We propose simultaneous inhibition of Gβ γ signaling in the heart and the adrenal gland as a novel therapeutic approach for heart failure (HF).
Fadia Kamal, D. Mickelsen, Katherine M. Wegman, Joshua G. Travers, J. Moalem, S. Hammes, A. Smrcka, B. Blaxall   +7 more
semanticscholar   +1 more source

Material Coupling in Hybrid Neuromorphic Devices: From Fundamentals to System‐Level Applications

Advanced Functional Materials, EarlyView.
Hybrid neuromorphic devices utilize heterointerfaces between emerging semiconductors, where charge transfer and trapping, ion or defect modulation, and photogating are translated into synaptic functions. This paper discusses coupling strategies that tailor interfacial electronic and ionic properties in organic semiconductors, metal oxides, two ...
Minsu So, Sunwoo Jeong, Youngmin Han, Fabrizio Torricelli, Hocheon Yoo, Junhwan Choi   +5 more
wiley   +1 more source

Endovascular treatment of fulminant idiopathic intracranial hypertension associated with intracranial venous sinus stenosis: one case report

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To report one case of fulminant idiopathic intracranial hypertension (FIIH) associated with intracranial venous sinus stenosis, and explore its clinical characteristics, diagnostic strategies, and the feasibility and efficacy of endovascular ...
LIU Shi-min, CAO Xian-min, WU Ling-feng, XIANG Zheng-bing, WEN An, CAO Wen-feng   +5 more
doaj   +1 more source

Protein Kinase G Iα Inhibits Pressure Overload–Induced Cardiac Remodeling and Is Required for the Cardioprotective Effect of Sildenafil In Vivo

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2012
Background Cyclic GMP (cGMP) signaling attenuates cardiac remodeling, but it is unclear which cGMP effectors mediate these effects and thus might serve as novel therapeutic targets.
R. Blanton, E. Takimoto, Angela M. Lane, M. Aronovitz, R. Piotrowski, R. Karas, D. Kass, M. Mendelsohn   +7 more
semanticscholar   +1 more source