Results 71 to 80 of about 13,489 (314)

ENDOSCOPIC DECOMPRESSION IN PATIENTS WITH ADJACENT SEGMENT STENOSIS AFTER LUMBAR ARTHRODESIS [PDF]

Coluna/Columna
Introduction and objective: Endoscopic decompression has emerged as an effective and minimally invasive therapeutic alternative for the management of adjacent-level stenosis in patients previously undergoing lumbar fusion.
Ricardo Esperidião, Adriano Passaglia Esperidião, Fernando Sepulveda Esperidião, Thiago Dantas Matos, Álvaro Diego Heredia Soarez, Marcelo Botelho Soares de Brito, Sonja Ellen Lobo, João Paulo Machado Bergamaschi   +7 more
doaj   +2 more sources

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

PATHOLOGICAL EVALUATION OF DORSAL ROOT GANGLIA AND SPINAL CORD AND SCIATIC NERVE FOLLOWING A CHRONIC CONSTRICTION INJURY OF THE SCIATIC NERVE IN RATS [PDF]

Kafrelsheikh Veterinary Medical Journal, 2019
Objective: To study pathological changes on spinal cord and dorsal root ganglia (DRG) and sciatic nerve itself after sciatic nerve injury in rats Design: Randomized experimental study Procedure:  Rats were randomly divided into two main groups. Control group (25 rats) without any treatment and treated group (n=50) with induced chronic constriction ...
Al-Shimaa E Elsayed, Walaa F Awadin, Marwa E Abass, Mohamed F Hamed   +3 more
openaire   +1 more source

Imaging of stone disease in pregnancy [PDF]

, 2013
Renal colic is the most frequent non-obstetric cause for abdominal pain and subsequent hospitalization during pregnancy. Intervention is necessary in patients who do not respond to conservative treatment.
BRUNELLI, Roberto, POLETTINI, Elisabetta, Francesca Laghi, FRAMARINO DEI MALATESTA, Marialuisa, Gabriele Masselli, DERME, MARTINA, GUALDI, GIANFRANCO   +6 more
core   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Selumetinib, an Oral Anti-Neoplastic Drug, May Attenuate Cardiac Hypertrophy via Targeting the ERK Pathway. [PDF]

, 2016
AimsAlthough extracellular-regulated kinases (ERK) are a well-known central mediator in cardiac hypertrophy, no clinically available ERK antagonist has been tested for preventing cardiac hypertrophy.
Dan Long, Chen, Z, Huawei Cai, Zhongxiu Chen, You, G, Zhang, Qiuping, Li, Y., Fangbo Luo, Hao Yang, Li, C, Yajiao Li, Rao, L, Shengfu Li, Cai, H, Chen Li, Long, D, Lihong Chen, Qiuping Zhang, Chen, L., Luo, F, Li Rao, Yang, H, Li, S, Guiying You   +23 more
core   +1 more source

Plastias de estenoses de intestino delgado na doença de Crohn: resultados imediatos e tardios Crohn’s disease small bowel strictureplasties: early and late results

Arquivos de Gastroenterologia, 2007
RACIONAL: As enteroplastias constituem alternativa cirúrgica no tratamento da estenose da doença de Crohn. OBJETIVO: Analisar, retrospectivamente, a evolução precoce e tardia do tratamento cirúrgico das estenoses do intestino delgado, segmento ileocecal ...
Maria de Lourdes Setsuko Ayrizono, Raquel Franco Leal, Cláudio Saddy Rodrigues Coy, João José Fagundes, Juvenal Ricardo Navarro Góes   +4 more
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Image_2_Inhibiting Receptor of Advanced Glycation End Products Attenuates Pressure Overload-Induced Cardiac Dysfunction by Preventing Excessive Autophagy.JPEG [PDF]

, 2018
The receptor for advanced glycation end products (RAGE) is involved in heart failure (HF) by mediating diverse pathologic processes, including the promotion of inflammation and autophagy.
Cui Yan (3820771), Zhongqi Yang (703895), Jiajia Wang (157207), Zheng Zhou (152309), Yusheng Huang (5780705), Birong Liang (5780702), Wenbin Gao (825538), Lingjun Wang (4516606), Zhaorui Wen (5780708), Yang Chen (9737), Lu Zhang (50563), Lu Lu (392), Shaoxiang Xian (4516615)   +12 more
core   +1 more source